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Janey WillisHello, I am Janey Willis, ISN News Director and ISN Asst. Webmaster. David Becker, ISN Assistant News Guide researches our Autoimmune News section. Jeannie McClelland, ISN Assistant News Guide, researches Scleroderma Medical and Media News. Assistant News Guide Lisa Bulman posts these stories to our Sclero Forums.
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October 2009
Cutaneous Vasculitis Associated With Interferon [beta]-1b ((IFN-β)-1b) Treatment for Multiple Sclerosis. Isolated lymphocytic cutaneous vasculitis linked to IFN-β-1b therapy is suspected as a new association. J. Szilasiová, MD. Clinical Neuropharmacology. October 2009. (Also see: Treatment for MS)
Fifteen-year experience of pediatric-onset mixed connective tissue disease (MCTD). The aim of this study was to investigate the initial clinical manifestations, laboratory data, complications, and outcomes of patients with pediatric-onset MCTD in Taiwan. The most common symptoms at disease onset were polyarthritis and Raynaud's phenomenon. Sclerodermatous changes of internal organs were a poor prognostic factor in our population. The clinical symptoms changed with time, and other symptoms encompassing the criteria for MCTD developed sequentially. (SpringerLink) Y. Tsai. Clinical Rheumatology. September 16 2009. (Also see: MCTD)
Work Disability in Patients with Ankylosing Spondylitis (AS). The prevalence of permanent work disability in Spanish patients with AS is significant, and the main factors related to it are age, disease duration, structural damage, and physical functioning. R. Ariza-Ariza. Journal of Rheumatology. October 15, 2009. (Also see: Ankylosing Spondylitis)
Adolescent Offspring of Mothers With Chronic Fatigue Syndrome (CFS). The higher prevalence of fatiguing states in offspring of CFS mothers, despite the lack of statistical significance, suggests that familial factors may potentially play a role in developing chronically fatiguing states. M. Smith, MD. Journal of Adolescent Health. October 13 2009. (Also see: CFS)
Dermatomyositis (DM) and small cell carcinoma of the bladder (SCCB). To the best of our knowledge, this is the first report of an association between SCCB and DM. L. Sagi, MD. Canadian Family Physician. October 2009. (Also see: Dermatomyositis)
The association between arthritis and psychiatric disorders; results from a longitudinal population-based study. Arthritis is associated with psychiatric disorders. Especially younger people (<45 years) with arthritis are at risk of developing a psychiatric disorder. H. Van’t Land. Journal of Psychosomatic Research. October 5 2009. (Also see: Complications with Arthritis)
Treatment of Adult Inflammatory Myositis With Rituximab: An Emerging Therapy for Refractory Patients. Early uncontrolled clinical experience indicates that rituximab may be a valuable therapeutic agent for treatment of refractory idiopathic inflammatory myopathy. S. Majmudar, D.O. Journal of Clinical Rheumatology. October 2009. Vol 15. Issue 7. pp 338-340. (Also see: Dermatomyositis)
Successful autologous stem cell transplantation (ASCT) in two patients with juvenile dermatomyositis (JDM). We demonstrate that ASCT is a therapeutic option with low toxicity for patients with severe, refractory JDM. (InformaWorld) U. Holzer. Scandanavian Journal of Rheumatology. September 24 2009. (Also see: Dermatomyositis)
“Strawberry like” gingivitis being the first sign of Wegener's granulomatosis (WG). This case emphasizes the importance to recognize the oral manifestation of WG to get proper medication as soon as possible and avoid serious systemic tissue damage. H. Ruokonen. European Journal of Internal Medicine. Volume 20, Issue 6, Pages 651-653 (October 2009). (Also see: Wegener's Granulomatosis)
Wegener’s granulomatosis (WG) presenting with life-threatening lung hemorrhage in a 7-year-old child. When a diffuse alveolar hemorrhage syndrome is demonstrated, WG should be considered among the main etiologies even in a relatively young child without a clinically suggestive history. (SpringerLink) S. Esposito. Rheumatology International. September 24 2009. (Also see: Wegener's Granulomatosis)
Active and Latent Tuberculosis (TB) in Patients With Systemic Lupus Erythematosus (SLE) Living in the United States. This study documents the demographic, clinical, and laboratory characteristics and outcomes of patients with SLE and latent tuberculosis infection (LTBI) or active TB in an ethnically diverse clinic. A significant number of patients with SLE in a county clinic population in the United States had LTBI or TB. A. Chu, MD. Journal of Clinical Rheumatology. August 2009. (Also see: Lupus)
Prevalence, predictors and outcome of vascular damage in systemic lupus erythematosus (SLE). Vascular events (VE) occurred in 26% of SLE patients, predominantly as atherothrombotic disease. VE prevalence increased linearly over time leading to a four-fold risk of mortality. (SageJournals) A. Becker-Merok. Lupus. Vol. 18, No. 6, 508-515. April 2009. (Also see: Lupus and Vasculitis)
Systemic lupus erythematosus (SLE) and the risk of cardiovascular disease: Results from the nurses' health study. In this prospective population-based study, we found a statistically significant >2-fold increased risk of cardiovascular disease among participants with SLE. (PubMed) AE Hak. Arthritis Rheum. September 29 2009. (Also see: SLE and Heart Disease)
25-hydroxyvitamin D and cardiovascular risk factors in women with systemic lupus erythematosus (SLE). This study demonstrates that vitamin D levels are low in women with SLE and significant associations exist with selected cardiovascular risk factors, although most of these associations can be explained by Body Mass Index. (PubMed) PW Wu. Arthritis Rheum. September 29 2009. (Also see: SLE and Heart Disease)
 
Go to Autoimmune News: September 2009
 
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