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Autoimmune Archive
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September 2013 Autoimmune News

Cardiovascular (CV) morbidity and mortality in psoriasis and psoriatic arthritis: a systematic literature review. There may be a small, but significant increased risk of cardiovascular events, but not of CV mortality in psoriasis and PsA patients. Journal of the European Academy of Dermatology and Venereology, 11 July 2013. (Also see Psoriasis and Psoriatic Arthritis)

Latest advances in connective tissue disorders. Genetic studies suggest a role for the innate immune system in disease pathogenesis, suggesting further future targets for biological therapies over the next few years. Therapeutic Advances in Musculoskeletal Disease, 2013 August; 5(4): 234-249. (Also see Connective Tissue Disease)

Myositis-specific and myositis-associated autoantibody profiles and their clinical associations in a large series of patients with polymyositis and dermatomyositis. Anti-Ro-52 was correlated with pulmonary disorders in dermatomyositis, whereas Anti-Jo-1 was correlated with pulmonary alterations in polymyositis. Clinics, 2013 July; 68(7): 909-914. (Also see Dermatomyositis and Polymyositis and Autoantibodies)

Lipid and lipoprotein levels and trends in rheumatoid arthritis (RA) compared to the general population. RA patients appear to have an overall lower total cholesterol and low density lipoprotein than the general population, despite the general overall risk of cardiovascular disease in RA from observational studies. PubMed, Arthritis Care Res, 2013 Aug 7. (Also see Rheumatoid Arthritis)

Prevalence, extent and composition of coronary plaque in patients with rheumatoid arthritis without symptoms or prior diagnosis of coronary artery disease. RA patients without coronary artery disease have higher prevalence, extent, and severity of all types of coronary plaque. PubMed, Ann Rheum Dis, 2013 Jul 25. (Also see Rheumatoid Arthritis)

Sarcoidosis: Immunopathogenesis and Immunological Markers. Despite extensive research, sarcoidosis remains a disease with undetermined aetiology. As such, the diagnosis of sarcoidosis remains a vexing clinical challenge. International Journal of Chronic Diseases, 17 June 2013. (Also see Sarcoidosis)

Natural killer (NK) cells in human autoimmune disorders. NK cells are innate lymphocytes that play a critical role in early host defense against viruses. PubMed, Arthritis Res Ther, 2013 Jul 11. (Also see Causes of Scleroderma: B cells and T Cells)

Delta neutrophil index (DNI) as a marker for differential diagnosis between flare and infection in febrile systemic lupus erythematosus (SLE) patients. Fever is a common symptom of systemic lupus erythematosus (SLE), and because of this it is difficult to discriminate between SLE flare and infection. DNI may be a marker to differentiate infections from SLE flares in febrile SLE patients. PubMed, Lupus, 2013 Aug 9. (Also see Lupus Symptoms)

Go to Autoimmune News: August 2013
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