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March 2015 Autoimmune News

Sonographic assessment of interstitial lung disease in patients with rheumatoid arthritis, systemic sclerosis and systemic lupus erythematosus. Transthoracic ultrasound of the lung might be a sensitive non-invasive tool to observe early stage interstitial lung disease in rheumatic diseases. Clinical and Experimental Rheumatology, 01/29/2015. (Also see Diagnosis of Pulmonary Fibrosis)

Association Between Corrected QT (QTc) Interval and Inflammatory Cytokines in Rheumatoid Arthritis (RA). A lower inflammatory burden may protect against QTc prolongation in patients with RA. PubMed, J Rheumatol, 01/15/2015. (Also see Cytokines)

Assessment of Risks of Pulmonary Infection During 12 Months Following Immunosuppressive Treatment for Active Connective Tissue Diseases: A Large-scale Prospective Cohort Study. Physicians should be aware of the higher risks for corticosteroids of pulmonary infection than other immunosuppressants and assess these risk factors before immunosuppressive treatment. PubMed, J Rheumatol, 02/01/2015. (Also see Immunosuppressants and Steroids)

Chronic Obstructive Pulmonary Disease Is Common in Never-smoking Patients with Primary Sjögren Syndrome (pSS). An obstructive pattern was the predominant pulmonary function test finding in patients with pSS, which suggest that superimposed restrictive lung disease per se is involved in the development of COPD. PubMed, J Rheumatol, 01/15/2015. (Also see Sjögren's Symptoms)

Decreased diffusion capacity on lung function testing in asymptomatic patients with systemic lupus erythematosus (SLE) does not predict future lung disease. A finding of low diffusion capacity in asymptomatic patients with SLE, with or without antiphospholipid syndrome, does not necessarily require further evaluation and imaging and may improve spontaneously over time. PubMed, Lupus, 01/16/2015. (Also see Symptoms and Complications of Lupus)

Frequent involvement of central nervous system in primary Sjögren syndrome (pSS). Neurological involvement was the first symptom of pSS, emphasizing the importance of considering this diagnosis, especially in young females with neurological symptoms without other evident cause. PubMed, Rheumatol Int, 2015 Feb;35(2):289-94. (Also see Symptoms and Complications of Sjogren's Syndrome)

Nailfold capillaroscopic changes in dermatomyositis (DM) and polymyositis (PM). Significant differences were observed between PM and DM with higher frequency and mean score of nailfold videocapillaroscopy changes in DM. PubMed, Clin Rheumatol, 2015 Feb;34(2):279-84. (Also see Dermatomyositis and Polymyositis)

The effect of aerobic exercise training on fatigue in rheumatoid arthritis: a meta-analysis. There is evidence with low risk of bias that an aerobic exercise program is effective in reducing fatigue among patients with RA. PubMed, Arthritis Care Res (Hoboken), 01/26/2015. (Also see Treatments for Rheumatoid Arthritis)

Association of cardiorespiratory fitness (CRF) with pressure pain sensitivity and clinical pain in women with fibromyalgia (FM). CRF is associated with pressure pain sensitivity but not with clinical pain in women with FM. PubMed, Rheumatol Int, 12/31/2014. (Also see Fibromyalgia Research)

Systemic lupus erythematosus (SLE) is not a risk factor for poor outcomes after total hip and total knee arthroplasty. SLE was not an independent risk factor for poor short-term pain or function after either hip or knee arthroplasty. PubMed, Lupus, 01/16/2015. (Also see Systemic Lupus Erythematosus Research)

Go to Autoimmune News: February 2015
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