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July 2014 Scleroderma News

Dentists' Knowledge, Confidence Tied to Care for Scleroderma Patients. Dentists' awareness of protocols and complications associated with treating patients with scleroderma may help improve their oral health care. TuftsNow, Journal of Clinical Rheumatology, June 2014. (Also see Scleroderma Dental Involvement)

Risk of coronary artery disease (CAD) in patients with systemic sclerosis (SSc): a systematic review and meta-analysis. This study demonstrated a statistically significant increased CAD risk among patients with SSc. PubMed, Clin Rheumatol, 2014 May 25. (Also see Scleroderma Heart Involvement)

United Kingdom survey of current management of juvenile localized scleroderma. How monitoring tools are accessed, used and perceived by paediatric rheumatologists and dermatologists in the UK varies between and within clinician groups, as do treatment prescribing patterns and transition arrangements. PubMed, Rheumatology (Oxford), 2014 May 21. (Also see Juvenile Scleroderma Experts)

Impact of hand face disabilities on global disability and quality of life (QoL) in systemic sclerosis (SSc) patients. Diffuse SSc patients present higher global and local disability, and lower Health Related QoL in the Summary Physical Index than Limited SSc patients. PubMed, Clin Exp Rheumatol, 2014 May 21. (Also see Quality of Life with Scleroderma)

Scleroderma Renal Crisis (SRC). This study shows that dialysis is frequently indicated but can be stopped in about half of patients, mainly those with good blood pressure control. PubMed, J Rheumatol, 2014 Jun;41(6):1040-1048. (Also see Kidney Involvement: Dialysis)

Dysfunctional arteriovenous anastomoses (AVAs) in hands of systemic sclerosis (SSc) patients with digital ulcers (DU). In SSc patients with DU there is a dysfunction of the AVAs of the finger pulp and AVA dysfunction may be a part of autonomic dysfunction in SSc. PubMed, Clin Exp Rheumatol, 2014 May 21. (Also see Digital Ulcer Research)

Association between systemic sclerosis (SSc) and bone mineral density (BMD) based on twelve observational studies. We conclude that patients with SSc may have a lower BMD level than healthy controls. PubMed, Int J Rheum Dis, 2014 Jun 4. (Also see Osteoporosis in Scleroderma: Bone Density)

Telemedicine Applied to Kinesiotherapy for Hand Dysfunction in Patients with Systemic Sclerosis and Rheumatoid Arthritis: Recovery of Movement and Telemonitoring Technology. Telemonitoring of self-administered kinesiotherapy programs is a promising approach to the rehabilitation of hand functions in patients with rheumatic disease. PubMed, J Rheumatol, 2014 Jun 1. (Also see Hand and Joint Involvement)

The expression profile of the toll-like receptor (TLR) family in scleroderma (SSc) dermal fibroblasts. TLR5 and TLR10 expression is increased in SSc fibroblasts. TLR5 itself may have suppressive effects on collagen expression, and its overexpression in SSc fibroblasts may be the negative feedback against tissue fibrosis. Clinical and Experimental Rheumatology, 14 June 2014. (Also see Skin Fibrosis)

A longitudinal study of ankle brachial pressure indices (ABPI) in a cohort of patients with systemic sclerosis (SSc). The severity of vascular disease in patients with SSc is associated with increasing age, smoking, limited cutaneous disease and positive anti-centromere antibodies. Reassuringly, in most patients ABPI remains stable over time. PubMed, Rheumatology (Oxford), 2014 Jun 6. (Also see Vascular Involvement and Digital Ulcers)

Go to Scleroderma Medical News: June 2014
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