Symptoms and Complications of Diabetes

Janey WillisHello, I am Janey Willis, ISN Guide to Diabetes. Type 1 Diabetes is an autoimmune disease, and Type 2 Diabetes is caused by risk factors such as lifestyle, ethnicity, age, and pregnancy. The majority of diabetics have Type 2. See Disclaimer.

Overview of Diabetes Symptoms
Erectile Dysfunction
Eye Complications
Heart Disease
Nerve Damage
Pancreas Disease and Diabetes
Pulmonary Complications
Renal Involvement
Skeletal Complications
Skin Complications
Thyroid Complications


Symptoms of Diabetes KaleidoscopeDiabetes may affect the heart, lungs, kidneys, gastrointestinal tract, bone, nervous system, thyroid gland, eyes, and skin. About 25% of diabetics also have symptoms of depression. (Also see Autoimmune Diseases and Overview of Diabetes)

Signs and Symptoms of Type 1 Diabetes. The onset of symptoms often appear after a flu-like illness and gradually intensify over the course of a few weeks. Symptoms include frequent urination, quick weight loss despite extreme hunger, blurred vision and extreme fatigue. MayoClinic.

Erectile Dysfunction

Pathophysiology of Diabetic Erectile Dysfunction. Diabetes mellitus is one of the predominant risk factors of erectile dysfunction (ED) and also one of the most difficult to treat. Medscape.

Eye Complications

Glaucoma, cataracts, and retinopathy are the more frequent eye complications with diabetes.

Diabetes Eye Care. Diabetes can harm your eyes. It can damage the small blood vessels in your retina, which is the back part of your eye. This condition is called diabetic retinopathy. Diabetes also increases your risk of having glaucoma, cataracts, and other eye problems. MedLinePlus.

Omega 3s Linked to Lower Risk of Diabetes Complications. Eating oily fish may lower a person's risk for diabetes–related vision problems, study suggests. Time Healthland, 08/18/2016.


Type 1 Gluten Free Diet Still Questionable. Recent research has determined that there is a relationship between type 1 diabetes and celiac disease, since both diseases result in the body's immune system mistakenly attacking itself. DiabetesHealth, 01/17/2015. (Also see Celiac Disease)

Heart Disease

Diabetes, Heart Disease, and Stroke. Having diabetes or prediabetes puts you at increased risk for heart disease and stroke. NDIC.

Liver Complications

Hepatic Arteriolosclerosis (HA): A Small-vessel Complication of Diabetes and Hypertension. HA is a small–vessel complication (microangiopathy) of the liver observed mainly in patients with diabetes who also have arterial hypertension. PubMed, American Journal of Surgical Pathology, 06/17/2015.

Nerve Damage

Prevent Diabetes Problems: Keep Your Nervous System Healthy. Research has shown that people who kept their blood glucose close to normal were able to lower their risk of nerve damage. National Diabetes Information Clearinghouse.

Pulmonary Complications

Assessment of pulmonary function in patients with type 2 diabetes mellitus: a case-control study. Among diabetics, odds of restrictive pattern of lung abnormality is four times that of non-diabetics. ScopeMed, 01/05/2015.

Renal Involvement

Preventing Diabetic Kidney Disease. High blood pressure, poor glucose (sugar) control, inherited tendency and diet increase the rick of developing diabetic kidney disease. National Kidney Foundation.

Skeletal Complications

The role of mineral and bone disorders (MBD) in the development and progression of cardiac and renal pathology in patients with type 1 diabetes mellitus of long duration. Development and progression of kidney dysfunction is accompanied by MBD, a significant factor in progression of cardiac pathology, which remains a major cause of mortality in this patient population. Diabetes Research and Clinical Practice, 05/03/2016.

Bone health in type 1 diabetes (T1D): focus on evaluation and treatment in clinical practice. The improvement of glycemic control has been suggested to have a beneficial effect on bone in T1D. PubMed, J Endocrinol Invest, 04/12/2015.

Diabetes mellitus (DM) risk factors in rheumatoid arthritis (RA): a systematic review and meta-analysis. RA is associated with increased risk of DM, including T1DM and T2DM. PubMed, Clin Exp Rheumatol, 2014 Dec 22. (Also see Rheumatoid Arthritis in Overlap)

Skin Complications

Diabetes: Skin Problems. For people with diabetes, having too much glucose (sugar) in their blood for a long time can cause serious complications, including skin problems. WebMD.

Thyroid Complications

Thyroid Disease and Diabetes. Diabetes and thyroid disease are both endocrine, or hormone, problems. When thyroid disease occurs in someone with diabetes, it can make blood glucose control more difficult. Diabetes Spectrum. (Also see Thyroid Disease)

Go to Causes of Diabetes
Most Recent Donors

Winn Schillberg
Reading Voices of Scleroderma Books: Diana Kramer.
Sharing Scleroderma Awareness Bracelets: Deb Martin, Brenda Miller, Vickie Risner.
Thanks to UNITED WAY donors of Central New Mexico and Snohomish County!

In Loving Memory

Patricia Ann Black: Marilyn Currier, Shelley Ensz, Richard Howitt, Gerald and Pat Ivanejko, Juno Beach Condo Association, Keith and Rosalyn Miller, and Elaine Wible.
Gayle Hedlin: Daniel and Joann Pepper and Nancy Smithberg.
Janet Paulmenn: Anonymous, Mary Jo Austin, Shelley Blaser, Susan Book, Dennis and Pat Clayton, Grace Cunha, Cindy Dorio, Michael and Patricia Donahue, Shelley Ensz, Nancy Falkenhagen, Jo Frowde, Alice Gigl, Margaret Hollywood, Karen Khalaf and Family, Susan Kvarantan, Bradley Lawrence, Jillyan Little, Donna Madge, Michele Maxson, Barry and Judith McCabe, John Moffett, My Tribute Foundation, Joan-Marie Permison, John Roberts, Margaret Roof, Maryellen Ryan, Mayalin and Kiralee Murphy, Nancy Settle-Murphy, and Bruce and Elizabeth Winter.


SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to:

International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA

Email [email protected] to request our Welcome email, or to report bad links or to update this page content.

TOLL FREE HOTLINE 800-564-7099
Free to U.S. and Canadian Callers. Ask for our Free Info Packet by mail or email!
Scleroderma, Pulmonary Arterial Hypertension, and related illnesses.
Privacy Policy.

The most important thing in the world to know about scleroderma is!
Donate Now
Copyright 1998-2016, International Scleroderma Network. AKA Scleroderma from A to Z and SCLERO.ORG. All Rights Reserved.