Diagnosis of systemic lupus can take many years. Even then, it is sometimes only diagnosed by autopsy.
It can help to keep on going to the same rheumatologist because switching doctors might only serve to further delay a diagnosis. It takes awhile (sometimes years or even decades) for certain symptoms to appear — and the accumulated symptoms may be quickly dismissed by a new doctor because they haven't personally witnessed them. (Also see Autoimmune Diseases and Overview of Lupus)
Serum Interleukin-34 Levels Are Elevated in Patients with Systemic Lupus Erythematosus (SLE). Serum IL-34 could be a candidate biomarker for SLE as there are elevated serum levels in treatment–naive SLE patients and a significant decrease after effective treatment was seen. PubMed, Molecules, 2016 Dec 28;22(1).
The diagnosis and management of the haematologic manifestations of lupus (SLE). In this review the most common and characteristic haematological manifestations of SLE patients are considered, focusing on their pathogenesis and management. PubMed, J Autoimmun, 2016 Nov;74:139-160.
Omics studies: their use in diagnosis and reclassification of systemic lupus erythematosus (SLE) and other systemic autoimmune diseases (SADs). This review summarizes the omics findings for SLE and propose ways of using the data for the identification of new biomarkers, finding new drugs and reclassifying patients not only with SLE, but also with other SADs. Rheumatology, 10/19/2016.
(Case Reports): Indicating the dilemma in diagnosing lupus cerebritis. Lupus Cerebritis should be included in the provisional diagnosis of a female patient of reproductive age group, who presents with complicated neurological manifestations and with no clear-cut clinical, pathological, or image finding. PubMed, J Family Med Prim Care.
Lupus Diagnosis Can Be Difficult. Lupus Foundation of America.
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