Myasthenia Gravis (MG)

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
What is Myasthenia Gravis?
Symptoms of MG
Pregnancy and MG
Scleroderma and MG
Treatments for MG
Research about MG
Personal Stories about MG

What is Myasthenia Gravis?

Myasthenia Gravis Kaleidoscope Myasthenia gravis is a rare autoimmune disease that affects voluntary muscles, causing them to weaken with activity.

Myasthenia gravis is a neuromuscular disorder characterized by variable weakness of voluntary muscles, which often improves with rest and worsens with activity. The condition is caused by an abnormal immune response. Medline Plus Dictionary.

Myasthenia gravis may be associated with other autoimmune diseases. Patients with family members who suffer from disorders such as rheumatoid arthritis, scleroderma, and lupus may have an increased risk for myasthenia gravis. Neurology Channel.

Myasthenia gravis is a chronic autoimmune neuromuscular disease characterized by varying degrees of weakness of the skeletal (voluntary) muscles of the body. National Institute of Neurological Disorders and Stroke.

Myasthenia Gravis Myasthenia gravis (MG) is the most common primary disorder of neuromuscular transmission. Myasthenia Gravis Foundation of America and James F. Howard, Jr., M.D.

Myasthenia Gravis. Medline Plus Health Information.

Ocular myasthenia: Diagnosis and treatment. Myasthenia gravis is a rare, auto-immune disorder of the neuromuscular junction. The diagnosis is essentially based on fluctuations in the time and topography of the ocular muscle weakness. Whereas some patients get better while on anticholinesterasic drugs alone, most of them will experience insufficient improvement and need steroids and/or immunosuppressant drugs. Stojkovic T. (PubMed) Rev Neurol (Paris), 2010 Nov 12.

Symptoms of Myasthenia Gravis

Symptoms of Myasthenia Gravis The primary symptoms of myasthenia gravis are that muscles are weak and quick to fatigue. These symptoms can take many forms, and the symptoms may be more or less severe for different people. Aetna InteliHealth.

Pregnancy and Myasthenia Gravis

Myasthenia Gravis (MG) may be associated with other autoimmune diseases. Patients with family members who suffer from disorders such as rheumatoid arthritis, scleroderma, and lupus may have an increased risk for myasthenia gravis. (Also see What is Scleroderma?)

Course and treatment of myasthenia gravis during pregnancy. Great significance is attached to the mode of delivery since it is still widely accepted that patients with myasthenia gravis have to deliver per elective caesarean section. This paper gives an overview and provides a basis for the medical care and individual counselling of patients with myasthenia gravis who want to start a family or are already pregnant. Klehmet J. (PubMed) Nervenarzt, 2010 Aug;81(8):956-62.

Scleroderma and Myasthenia Gravis

Myasthenia gravis and scleroderma: Two cases and a review of the literature. Myasthenia gravis is uncommon in patients with scleroderma, and when diagnosed is usually associated with previous use of d-penicillamine. Clinically, both myasthenia and scleroderma may present with fatigue, weakness and bulbar symptoms, so one of diagnoses may be delayed. PubMed, Clin Neurol Neurosurg. 2007 Feb 3. (Also see Clinical Trials: Negative Results)

Myasthenia Gravis (MG) may be associated with other autoimmune diseases. Patients with family members who suffer from disorders such as rheumatoid arthritis, scleroderma, and lupus may have an increased risk for myasthenia gravis. (Also see Autoimmune Diseases: Main Page and What is Scleroderma?)

Treatments for Myasthenia Gravis

AAN: Rituximab Effective in Myasthenia Gravis. Rituximab (Rituxan), the anti-CD20 antibody that decreases B-cell activation, slashed autoantibody titers and improved symptoms in patients with myasthenia gravis (MG) refractory to standard therapies. John Gever. Medpage Today. 04/14/10.

Research about Myasthenia Gravis

The role of TNFα induced protein 3 interacting protein 1(TNIP1) in the pathogenesis of myasthenia gravis among patients with thymoma. Reduced TNIP1 expression may have a role in the pathogenesis of MG for patients with thymoma and thymectomy may help to recover the expression of TNIP1 among such patients. PubMed, Zhonghua Yi Xue Yi Chuan Xue Za Zhi, 2016 Oct;33(5):615-8.

Acute presentation of autoimmune hepatitis in a patient with myasthenia gravis, thymoma, Hashimoto thyroiditis and connective tissue disorder. PubMed, Hepatol Res, 2012 Aug;42(8):835-9. (Also see Liver Involvement, and Hashimoto's Thyroiditis)

Personal Stories about Myasthenia Gravis

Papa V: Lupus, Antiphospholipid Syndrome, Myasthenia Gravis, and Scleroderma About thirty years passed, and then—BAM !—I got a heart blockage, stroke, liver biopsy due to elevated enzymes, skin rash, high blood pressure, very high ANA..

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