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Systemic Autoimmune Rheumatic Diseases

Author: Janey Willis. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview
Symptoms/Complications
Causes
Diagnosis
Antibodies
Treatments

Overview

Rheumatic KaleidoscopeSystemic autoimmune rheumatic diseases are different from most autoimmune diseases in that they affect many organs, cells or tissues simultaneously rather than just one. Examples of rheumatic diseases are systemic sclerosis (systemic scleroderma), lupus, rheumatoid arthritis, Sjögren's, dermatomyositis, and polymyositis. Examples of non-rheumatic diseases are diabetes, autoimmune hepatitis, autoimmune thyroid disease, and psoriasis.

The National Data Bank (NDB) for rheumatic diseases: Diagnosis List. If you have been diagnosed with one or more conditions from the following list, you are eligible to participate in NDB research. If you have a diagnosis for a rheumatic disease that you do not see listed, please contact us. The NDB for Rheumatic Disease. (Also see Research Registries)

Symptoms and Complications of Autoimmune Rheumatic Diseases

Ocular Involvement in Systemic Autoimmune Diseases. The aim of this review is to elucidate to non-ophthalmologists the major ocular complications of rheumatic diseases and their specific management and treatment options. PubMed, Clin Rev Allergy Immunol, 10/22/2015. (Also see Eye Involvement of Rheumatic Diseases)

Depression, anxiety, and quality of life in a large cohort of patients with rheumatic diseases: common, yet undertreated. For the management of depression and anxiety, an increased awareness among physicians dealing with rheumatologic patients is warranted in order to integrate detection and effective treatment of anxiety and depression into the routine clinical practice. PubMed, Clin Rheumatol, 2014 May 25. (Also see Depression)

Eye Involvement. ISN

Symptoms and Complications of Scleroderma. ISN.

Symptoms and Complications of Lupus. ISN.

Symptoms and Complications of Dermatomyositis and Polymyositis. ISN.

Symptoms and Complications of Sjögren's. ISN.

Symptoms and Complications of Rheumatoid Arthritis. ISN.

Causes

Enzyme identified as a major culprit of autoimmune diseases. Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report. Science Daily, 10/27/2015.

Diagnosis

Diagnosis of Scleroderma. ISN.

Diagnosisof Lupus. ISN.

Diagnosisof Dermatomyositis and Polymyositis. ISN.

Diagnosisof Sjögren's. ISN.

Diagnosisof Rheumatoid Arthritis. ISN.

Antibodies

Autoantibodies in Systemic Rheumatic Diseases. Specialized blood tests such as antinuclear antibody (ANA) tests are sometimes useful in the diagnosis or categorization of both localized and systemic scleroderma, as well as overlapping or other autoimmune diseases. ISN.

Treatments

Treatments for Rheumatic Diseases. ISN.

Therapeutic drug monitoring in rheumatic diseases: utile or futile? The therapeutic effect of most medications may be slow to manifest and studies in rheumatic diseases have so far failed to confirm a useful association between concentrations and disease control or drug toxicity. PubMed, Rheumatology, 2013 Nov 5.

Go to Rheumatoid Arthritis
 
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