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Graft-versus-Host Disease (GVHD)

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview
Causes
Diagnosis
Treatments
Patient Stories

Overview of Graft-versus-Host Disease (GVHD)

GVHD KaleidoscopeGraft-versus-Host Disease (GVHD) is an autoimmune response to foreign cells, such as from skin grafting, bone marrow transplants, stem cell transplants, blood transfusions, or organ transplants.

Causes of Graft-versus-Host Disease (GVHD)

Graft-versus-Host Disease - Causes. Graft-versus-host disease (GVHD) is a complication that can occur after a stem cell or bone marrow transplant in which the newly transplanted material attacks the transplant recipient's body. MedlinePlus.

Diagnosis of Graft-versus-Host Disease (GVHD)

Validation of International Chronic Ocular Graft-Versus-Host Disease (GVHD) Group Diagnostic Criteria as a Chronic Ocular GVHD–Specific Metric. The newly proposed International Chronic Ocular GVHD Consensus Group diagnostic criteria can be used reproducibly for the diagnosis and determination of severity of chronic ocular GVHD. PubMed, Cornea, 2017 Feb;36(2):258-263.

Bullous scleroderma-like changes in chronic graft-versus-host disease. Chronic cutaneous GVHD is categorized according to the type of skin lesions into lichenoid and sclerodermoid variants, but bullous scleroderma-like changes are exceptional. PubMed, J Eur Acad Dermatol Venereol.

Treatments for Graft-versus-Host Disease (GVHD)

A case of cutaneous lichen sclerosus et atrophicus (LSA) effectively treated by extracorporeal photochemotherapy (ECP). The fact that ECP is effective in LSA, graft-versus-host disease (GVHD), erosive lichen planus, and scleroderma strengthen the hypothesis that there is a common link between these four conditions. Wiley. Photodermatology, Photoimmunology & Photomedicine. (Also see Lichen Sclerosus)

Ultraviolet A1 phototherapy beyond morphea: experience in 83 patients. UVA1 phototherapy is effective and safe in the treatment of graft–versus–host disease, nephrogenic systemic fibrosis, systemic sclerosis, and mast cell disorders. PubMed, Photodermatol Photoimmunol Photomed, 2015 Nov;31(6):289-95. (Also see Skin Fibrosis and Morphea Treatments)

Patient Stories for Graft-versus-Host Disease (GVHD)

Blog: Jackie Sue We Love You. Jackie passed away on November 30th, 2011. Jackie had GVHD. The blog covered her progress after her mini-allo MUD transplant. Her transplant was the first one to be performed by the Mayo Clinic. Bruce and Jackie. (Also see Graft vs. Host Disease, GVHD)

Klaas: Scleroderma Graft-vs-Host Disease (GVHD) So I would like to know if, and when, I will be able to walk again…

(Spanish/Español) Klaas: Sclerodermia da GVHD Essiste un modo per capire se ci sono delle speranze e quali sono…

(Italiano) Fabiola: Paziente Affetta da Sclerodermia Morphea Dopo 5 anni si e' svegliata una sclero conseguenza pero' della GVHD (Graft Versus Host Disease) che viene dopo il trapianto di midollo…

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