Dendritic cells are involved in the regulation of the body's immune system response, and are thought to be a key to preventing or treating autoimmune diseases. (Also see: Causes of Scleroderma, What is Scleroderma?, Types of Scleroderma, and Systemic Sclerosis)
Contribution of Dendritic cells (DCs) to the autoimmune pathology of Systemic Lupus Erythematosus. In this review article the authors discuss the most relevant data relative to the contribution of DCs to the triggering of SLE. PubMed, Immunology, 07/17/2015.
An update on an immune system that goes awry in systemic sclerosis. We propose to approach SSc as a multistep immune-mediated disease that is in need of a therapeutic strategy designed to interfere with one or more aberrant molecular pathways. Targeting of dendritic cells could be such a target by which dampening the immune system could modify the course of SSc. Curr Opin Rheumatol, 2011 Aug 31.
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