Dendritic cells are involved in the regulation of the body's immune system response, and are thought to be a key to preventing or treating autoimmune diseases. (Also see: Causes of Scleroderma, What is Scleroderma?, Types of Scleroderma, and Systemic Sclerosis)
An update on an immune system that goes awry in systemic sclerosis. We propose to approach SSc as a multistep immune-mediated disease that is in need of a therapeutic strategy designed to interfere with one or more aberrant molecular pathways. Targeting of dendritic cells could be such a target by which dampening the immune system could modify the course of SSc. Curr Opin Rheumatol, 2011 Aug 31.
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