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Causes of Scleroderma: Vinyl Chloride

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer

Overview of Vinyl Chloride and Vinyl Chloride Disease (a scleroderma-like illness)

Exposure to vinyl chloride has been found to cause acroosteolysis, angiosarcoma, brain cancer, leukemia, liver disease, Raynaud's, scleroderma, and "vinyl chloride disease". It can cause scleroderma-like skin changes.

Synonyms and Trade Names for Vinyl Chloride: Chloroethene, Chloroethylene, Ethylene monochloride, Monochloroethene, Monochloroethylene, VC, Vinyl chloride monomer (VCM). NIOSH Pocket Guide to Hazardous Chemicals.

Vinyl Chloride Hazards Summary A small percentage of individuals occupationally exposed to high levels of vinyl chloride in air have developed a set of symptoms termed "vinyl chloride disease," which is characterized by Raynaud's phenomenon (fingers blanch and numbness and discomfort are experienced upon exposure to the cold), changes in the bones at the end of the fingers, joint and muscle pain, and scleroderma-like skin changes (thickening of the skin, decreased elasticity, and slight edema). U.S. Environmental Protection Agency.

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