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Sleep Disorders and Illness

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview of Sleep Disorders and Illness
Suggestions for Better Sleep
Sleep Disorders and Genetics
Sleep Spindles
Immune System and Circadian Clocks
Infections and Sleep
Inflammation and Sleep
Sleep Apnea

Overview of Sleep Disorders and Illness

With the onset of chronic illness, a good night's sleep is often the first thing to go. Sometimes poor sleep is a precursor to illness, and other times it is a result.

Idiopathic hypersomnia (unexplained daytime sleepiness). Hypersomnia means excessive sleep or sleepiness that interferes with everyday life. NHS Choices.

Too much sleep is ‘AS bad for your health as smoking and drinking alcohol’. Sleeping more than nine hours a night — combined with sitting too much during the day and a lack of exercise — can be just as bad for you as smoking and drinking alcohol. Mail Online, 12/12/2015.

Sleep as a biomarker for depression. Research on sleep in depression has provided several valuable biomarkers that are related to increased risk for depression, show worsening during depressive episode, and are related to treatment outcome and relapse risk during remission phase. PubMed, Int Rev Psychiatry, 2013 Oct;25(5):632-45. (Also see Depression)

Sleep Problems in Patients with Rheumatoid Arthritis (RA). Poor control of RA is associated with a reduction in sleep quality and decreased daytime sleepiness, which is likely explained by pain-related alertness. PubMed, J Rheumatol, 2013 Dec 1. (Also see Rheumatoid Arthritis)

Suggestions for Better Sleep

Physical activity, sleep quality, and self–reported fatigue across the adult lifespan. These results support the hypothesis that physical activity may be associated with sleep quality in older adults, and suggest that improved sleep may mitigate self–reported fatigue in older adults in a manner that is independent of activity. PubMed, Exp Gerontol, 02/04/2016. (Also see Fatigue)

Are pets in the bedroom a problem for sleep? There are many potential health benefits to pet ownership, but a good night’s sleep may not necessarily be one of them, a small study suggests. Reuters Health, 11/20/2015.

Does Your Diet Influence How Well You Sleep? Poor sleeping habits can lead to overeating, but can unhealthy diets keep you up at night? Time Healthland. 02/07/2013.

Sleep and Genetics

People with a certain gene, HLA DQB1*0602, are at high risk for insomnia, fatigue, and narcolepsy.

How Long You Sleep May Be in Your Genes. The amount of time people spend sleeping is linked with two regions of their DNA, a study suggests. Livescience, 12/02/2014.

Sleep Spindles

Sleep Spindles: Where They Come From, What They Do. A highlight in the search of roles for sleep spindles is the repeated finding that spindles correlate with memory consolidation in humans and animals. PubMed, Neuroscientist. 2013 Aug 27;20(3):243-256.

Immune System and Circadian Clocks

Researchers are exploring the relationship between insufficient sleep and poor health.

Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Insufficient sleep and circadian rhythm disruption are associated with negative health outcomes, but the mechanisms involved remain largely unexplored. PNAS. 01/23/2013.

Infections and Sleep

(Case Report) Can more sleep help fight off colds? A new study suggests that people who lose just a bit of sleep, or those who have poor quality sleep, are more likely to get sick after being exposed to a cold virus than those who get more shut-eye. CNN Health.

Inflammation and Sleep

Sleep Impairment: A Trigger for Relapse in IBD? Certain cytokines are known to interfere with sleep, and sleep deprivation results in upregulation of cytokines. Medscape, 01/23/2014.

Vascular Inflammation and Sleep Disordered Breathing in a Community-Based Cohort. Sleep disordered breathing is associated with higher levels of interleukin-6, a marker of myocardial infarction risk and mortality. Sleep, Vol 36, Issue 05, 2013.

Sleep Apnea

Sleep apnea causes people to frequently stop breathing during sleep. The episodes can last for several seconds or longer. It results in unrefreshing sleep which can cause daytime sleepiness and fatigue. It is associated with many diseases, including high blood pressure, obesity, and heart problems. It is diagnosed with sleep laboratory studies, and typically treated with a CPAP machine, however other methods may include surgery, oxygen, medications, and throat exercises. ISN.

Overview of Sleep Apnea?
Sleep Apnea and Autoimmune Diseases
Complications
Diagnosis
Treatments
Patient Stories
Go to Sleep Apnea
 
 

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Copyright 1998-2016, International Scleroderma Network. AKA Scleroderma from A to Z and SCLERO.ORG. All Rights Reserved.