SCLERO.ORG
Search

Research about Scleroderma Cardiac (Heart) Involvement

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Antibodies
Autoimmunity and Heart Disease
Causes of Heart Disease

Antibodies

Hypothyroidism Contributes to Increased Triglyceride Levels Among Patients with Systemic Sclerosis (SSc). In a cohort of 49 patients with diffuse SSc clinical and laboratory features of hypothyroidism were observed in 27% of the patients and increased triglyceride levels in more than 55%. It is estimated that about half of SSc patients experience overt or latent hypothyroidism. J. Rheumatol, [2006] April;33:827. (Also see Thyroid Disease and Lipoprotein[a] and Thrombotic Complications)

Autoimmunity and Heart Disease

Idiopathic pulmonary fibrosis (IPF) and coronary artery disease. A more extensive cardiopulmonary exercise test should be performed for better management of IPF patients, not only with the goal of identifying useful prognostic parameters, but also to detect potentially treatable cardiovascular alterations earlier. Multidisciplinary Respiratory Medicine 2014, 9:31. (Also see Pulmonary Fibrosis Correlations)

Causes of Heart Disease in Systemic Autoimmune Diseases

Prognostic value of N-terminal natriuretic peptides (NT-proANP) in systemic sclerosis (SSc): a single centre study. The high negative predictive value of natriuretic peptides supports the more extensive use in identifying SSc patients with high risk of future cardiac involvement. PubMed, Clin Exp Rheumatol, 2014 Nov-Dec;32 Suppl 6(6):75-81.

Autonomic dysfunction in patients with systemic sclerosis: Correlation with intrarenal arterial stiffness. Autonomic dysfunction (AD) is a feature of SSc, starting early in the disease and possibly preceding the development of fibrosis. International Journal Of Cardiology, 09/04/2014.

Pericardial involvement in systemic autoimmune diseases. On rare occasions, pericardial effusion and/or pericarditis may be the first clues of a systemic inflammatory disease or a manifestation of a known systemic disease. In these cases, pericardial involvement generally reflects the activity of the systemic disease. Wolters Kluwer Health, 12/14/2012.

Go to Scleroderma Cardiac Involvement
 
Most Recent Donors

Winn Schillberg
Reading Voices of Scleroderma Books: Diana Kramer.
Sharing Scleroderma Awareness Bracelets: Deb Martin, Brenda Miller, Vickie Risner.
Thanks to UNITED WAY donors of Central New Mexico and Snohomish County!

In Loving Memory

Patricia Ann Black: Marilyn Currier, Shelley Ensz, Richard Howitt, Gerald and Pat Ivanejko, Juno Beach Condo Association, Keith and Rosalyn Miller, and Elaine Wible.
Gayle Hedlin: Daniel and Joann Pepper and Nancy Smithberg.
Janet Paulmenn: Anonymous, Mary Jo Austin, Shelley Blaser, Susan Book, Dennis and Pat Clayton, Grace Cunha, Cindy Dorio, Michael and Patricia Donahue, Shelley Ensz, Nancy Falkenhagen, Jo Frowde, Alice Gigl, Margaret Hollywood, Karen Khalaf and Family, Susan Kvarantan, Bradley Lawrence, Jillyan Little, Donna Madge, Michele Maxson, Barry and Judith McCabe, John Moffett, My Tribute Foundation, Joan-Marie Permison, John Roberts, Margaret Roof, Maryellen Ryan, Mayalin and Kiralee Murphy, Nancy Settle-Murphy, and Bruce and Elizabeth Winter.

 

SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team, or Volunteer. Donations may also be mailed to:

International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA

Email [email protected] to request our Welcome email, or to report bad links or to update this page content.

TOLL FREE HOTLINE 800-564-7099
Free to U.S. and Canadian Callers. Ask for our Free Info Packet by mail or email!
Scleroderma, Pulmonary Arterial Hypertension, and related illnesses.
Privacy Policy.

 
The most important thing in the world to know about scleroderma is sclero.org!
Donate Now
Copyright 1998-2016, International Scleroderma Network. AKA Scleroderma from A to Z and SCLERO.ORG. All Rights Reserved.