Periodontal Disease and Systemic Sclerosis (SSc)

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Bone Resorption


Periodontal Pick by Shelley EnszDue to dry mouth and hygiene difficulties, scleroderma patients are at increased risk for periodontal disease. Symptoms of periodontal disease include toothache, loose teeth, bad breath, and painful, red, and swollen bleeding gums. Treatment may include medications and having a dental hygenist scrape plaque off the roots of the teeth. (Also see Scleroderma Dental Involvement, What is Scleroderma?, Types of Scleroderma, and Systemic Sclerosis)

Autoimmunity and Periodontal Disease

Hair Loss Linked to Tooth Infections. Following the link between white blood cells, infection, and alopecia, scientists are now studying the effects of tooth infection, and the increase in white blood cells, to sudden hair loss. HairLossExpert, 06/21/2014. (Also see Alopecia)

Early signs of arthritis can be found in the mouth. A common gum disease may indicate a person’s risk of developing rheumatoid arthritis later in life. The University of Adelaide News, 05/04/2015.

Involvement of Autoimmunity in the Pathogenesis of Aggressive Periodontitis. The aim of this study was to investigate the involvement of autoimmune reactions to native and post-translationally modified extracellular matrix components in the pathogenesis of periodontitis. Hendler A J. (PubMed) Dent Res, 2010 Oct 12.

Bone Resorption

Osteolysis Affecting the Jaws in Systemic Sclerosis: Clinical and Osseous Changes Based on a Case Presentation. Based on the presented case and the neglection of the oral findings, early monitoring of oral changes in patients with this condition is mandatory and may improve their living conditions. PMC, Clin Med Insights Arthritis Musculoskelet Disord, 2015; 8: 65–67.

Mechanisms of Bone Resorption in Periodontitis. Bone resorption via osteoclasts and bone formation via osteoblasts are coupled, and their dysregulation is associated with numerous diseases of the skeletal system. Journal of Immunology Research, 12/13/2014. (Also see Bone Resorption)

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