Scleroderma Treatments and Clinical Trials

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Symptoms and Treatments
Scleroderma Experts
Scleroderma Research
Open Enrollments
Completed: Positive
Completed: Awaiting
Completed: Inconclusive
Completed: Negative


Participating in clinical trials for scleroderma and related symptoms is a way to advance scientific understanding of the disease and its potential treatments.

Clinical Trials for Scleroderma. Completed, activie and not recruiting, not yet recruiting, and recruiting.

Systemic Scleroderma Symptoms. Most of the proven or accepted treatments for scleroderma symptoms are found on the individual symptom pages. See the master listing of scleroderma symptoms or use our internal site search (above) to find the latest information and treatments. The best recommendation we can give is for scleroderma patients to consult a scleroderma expert, since it is a rare illness with unusual complications and unique treatment concerns. ISN.

Types of Scleroderma. Symptoms, treatments and prognosis for scleroderma vary drastically based on the type of scleroderma. ISN.

Scleroderma and Alternative Medicine, Herbs, and Vitamins. Some helpful ideas to try along with tips on therapies to avoid. ISN.

Scleroderma Experts

See a scleroderma expert to apply for enrollment in clinical trials and for the best possible clinical care.

Scleroderma Experts. Scleroderma is a rare disease so it is best to consult an expert as soon as possible to be assured of the latest treatment information, and for the opportunity to enroll in clinical trials. ISN.

Expert Lists:
United States
U.S. & World
Research Fund
ISN Medical Advisory Board
Finding Rheumatologist
Physician/Patient Relationships
About Doctors and Clinics

Scleroderma Research

Scleroderma Research covers potential causes of scleroderma, the history of scleroderma, postmortem resources for such issues as autopsies and cadavers, research registries for patients and family members, plus scleroderma treatments and clinical trials. ISN.

Causes of Scleroderma
History of Scleroderma
Postmortem Resources
Scleroderma Research Registries
Treatments and Clinical Trials

Open Enrollments

Scleroderma Clinical Trials, Open Enrollments. Excitement is brewing in the field of scleroderma research, as every day seems to bring new advances regarding possible causes of scleroderma as well as improved treatments. ISN.

Symptom Treatments
Actemra (Tocilizumab)
ADRC Injections/STAR Trial
Allogenic Stem Cell Transplant
AM152 (Lysophosphatidic Acid 1)
Ambrisentan for Scleroderma
Bardoxolone by Reata
BEAT Clinical Trial
Cyclophosphamide and rATG With Hematopoietic Stem Cell Support
Fludarabine/Donor Peripheral SCT
Hydrogen Sulphide
Nilotnib (Tasigna)
Nintedanib (OFEV)
Opsumit® (Macitentan)
Rituximab for PAH
SAR156597 for IPF (Sanofi)
Scleroderma Lung Study II
SPIN: Patient-centered Network
Stem Cell Transplants for Scleroderma
Tracleer® (Bosentan)
Twins and Siblings Study
Velcade® (Bortezomib)

Completed, Positive Results

Scleroderma Clinical Trials, Completed, Positive Results.Excitement is brewing in the field of scleroderma research, as every day seems to bring new advances regarding possible causes of scleroderma as well as improved treatments. ISN.

Combination Therapies
Electrophoresis with Ximedon
PUVA/UVA-1 and Phototherapy
Rituximab (Rituxan)
Stem Cell Transplant
Urokinase Therapy

Completed, Awaiting Results

Scleroderma Clinical Trials, Completed, Awaiting Results. ISN.

Psychological Treatments
Sildenafil in PH
SCOT Trial

Completed, Inconclusive Results

Bovine Collagen DMSO/MSM

Completed, Negative Results

Scleroderma Clinical Trials, Completed, Negative Results. Disproven treatments for systemic scleroderma include alpha interferon, imatinib mesylate, minocycline (the "antibiotic cure"), penicillamine, and relaxin. ISN.

Alpha Interferon
Anti-TGFß1 (CAT 192)
Gamma Interferon
Imatinib Mesylate (Gleevec)
Minocycline (Antibiotic)
Penicillamine, Cuprimine, Depen

Also See

Sjögren's Treatments & Clinical Trials
Scleroderma Medical News

Scleroderma Symptoms (treatments are listed for each symptom)

Go to Current Trials: Open Enrollment
Most Recent Donors

Winn Schillberg
Reading Voices of Scleroderma Books: Diana Kramer.
Sharing Scleroderma Awareness Bracelets: Deb Martin, Brenda Miller, Vickie Risner.
Thanks to UNITED WAY donors of Central New Mexico and Snohomish County!

In Loving Memory

Patricia Ann Black: Marilyn Currier, Shelley Ensz, Richard Howitt, Gerald and Pat Ivanejko, Juno Beach Condo Association, Keith and Rosalyn Miller, and Elaine Wible.
Gayle Hedlin: Daniel and Joann Pepper and Nancy Smithberg.
Janet Paulmenn: Anonymous, Mary Jo Austin, Shelley Blaser, Susan Book, Dennis and Pat Clayton, Grace Cunha, Cindy Dorio, Michael and Patricia Donahue, Shelley Ensz, Nancy Falkenhagen, Jo Frowde, Alice Gigl, Margaret Hollywood, Karen Khalaf and Family, Susan Kvarantan, Bradley Lawrence, Jillyan Little, Donna Madge, Michele Maxson, Barry and Judith McCabe, John Moffett, My Tribute Foundation, Joan-Marie Permison, John Roberts, Margaret Roof, Maryellen Ryan, Mayalin and Kiralee Murphy, Nancy Settle-Murphy, and Bruce and Elizabeth Winter.


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