Sometimes complications (especially rare ones) are acknowledged for medications only after they have been in widespread use.
That's why it is a good idea to regularly check all of your medications for FDA black box warnings, voluntary manufacturer recalls, class action lawsuits, and also for changes in instructions or side effect listings.
We track some of the medications that are more commonly used by scleroderma patients and list new or recent warnings here. (Also see What is Scleroderma?, Medical Overview, and Medications for Scleroderma, Arthritis, Autoimmune and Rheumatic Diseases)
Cautious ACE Inhibitor Use Needed in Scleroderma. This study suggests that ACE inhibitors should be used with great caution in patients with scleroderma, particularly early in disease when the risk of renal crisis is greatest. MedPageToday. 11/11/12. (Also see Kidney Involvement and Hypertension)
FDA Warns of Fracture Risk From Acid Reflux Drugs. Popular PPI antacids -- Aciphex, Dexilant, Nexium, Prevacid, Prilosec, Protonix, Vimovo, and Zegerid -- raise the risk of bone fracture, especially when used for a year or more or at high doses, the FDA warns. Danial J. DeNoon. WebMD Health News. May 25, 2010 (Also see GERD and Reflux Treatments)
Scleroderma Clinical Trials and Open Enrollments Includes proven treatments, unproven, open enrollments, pending results, and research registries. ISN.
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