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Sleep Disorders and Illness

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview of Sleep Disorders and Illness
Suggestions for Better Sleep
Sleep Disorders and Genetics
Sleep Spindles
Immune System and Circadian Clocks
Infections and Sleep
Inflammation and Sleep
Sleep Apnea

Overview of Sleep Disorders and Illness

With the onset of chronic illness, a good night's sleep is often the first thing to go. Sometimes poor sleep is a precursor to illness, and other times it is a result.
Sleep as a biomarker for depression. Research on sleep in depression has provided several valuable biomarkers that are related to increased risk for depression, show worsening during depressive episode, and are related to treatment outcome and relapse risk during remission phase. PubMed, Int Rev Psychiatry, 2013 Oct;25(5):632-45. (Also see: Depression)
Sleep Problems in Patients with Rheumatoid Arthritis (RA). Poor control of RA is associated with a reduction in sleep quality and decreased daytime sleepiness, which is likely explained by pain-related alertness. PubMed, J Rheumatol, 2013 Dec 1. (Also see: Rheumatoid Arthritis)
Too little sleep linked to heart disease risk. In a large U.S. study, people who tended to get less than six hours of sleep nightly were more likely to have high blood pressure, high cholesterol, diabetes and to be obese. Chicago Tribune, 11/06/2013.

Suggestions for Better Sleep

Does Your Diet Influence How Well You Sleep? Poor sleeping habits can lead to overeating, but can unhealthy diets keep you up at night? Time Healthland. 02/07/2013.
Simple Rules for Better Sleep. This sounds way too good to be true: a quick, effective solution to the insomnia that plagues an estimated 15 to 30 percent of older adults — without drugs, without even needing to consult a physician. Paula Span. (Hcanorthhouston). Home Care. 03/23/12.

Sleep and Genetics

People with a certain gene, HLA DQB1*0602, are at high risk for insomnia, fatigue, and narcolepsy.
Sleepiness Could Be in Our Genes. The researchers found that after several nights of restricted sleep, healthy adults who carried a particular gene variant called DQB1*0602 were sleepier and more fatigued during the day, and had more fragmented sleep, than non-carriers.Medical News Today. 10/27/10.

Sleep Spindles

Light sleeper or sleep through anything? Thank (or blame) the brain. Why can some people sleep through car alarms and thunderstorms when others wake up at the sound of footsteps? Researchers believe they've found the answer tucked in sleep spindles, or bursts of brain activity that occur only during sleep. Stephanie Steinberg, USA TODAY. August 2010.

Immune System and Circadian Clocks

Researchers are exploring the relationship between insufficient sleep and poor health.
Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Insufficient sleep and circadian rhythm disruption are associated with negative health outcomes, but the mechanisms involved remain largely unexplored. PNAS. 01/23/2013.

Infections and Sleep

Study: Can more sleep help fight off colds? A new study suggests that people who lose just a bit of sleep, or those who have poor quality sleep, are more likely to get sick after being exposed to a cold virus than those who get more shut-eye. CNN Health. 01/13/09.

Inflammation and Sleep

Sleep Impairment: A Trigger for Relapse in IBD? Certain cytokines are known to interfere with sleep, and sleep deprivation results in upregulation of cytokines. Medscape, 01/23/2014.
Vascular Inflammation and Sleep Disordered Breathing in a Community-Based Cohort. Sleep disordered breathing is associated with higher levels of interleukin-6, a marker of myocardial infarction risk and mortality. Sleep, Vol 36, Issue 05, 2013.

Sleep Apnea

Sleep apnea causes people to frequently stop breathing during sleep. The episodes can last for several seconds or longer. It results in unrefreshing sleep which can cause daytime sleepiness and fatigue. It is associated with many diseases, including high blood pressure, obesity, and heart problems. It is diagnosed with sleep laboratory studies, and typically treated with a CPAP machine, however other methods may include surgery, oxygen, medications, and throat exercises. ISN.
Overview of Sleep Apnea?
Sleep Apnea and Autoimmune Diseases
Complications
Diagnosis
Treatments
Patient Stories
 
Go to Sleep Apnea
 

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