Wonder Drug in Sclero Forums (MAIN) Posted February 7, 2007 · Report reply Hi Peanut,Sometimes prednisone might be unavoidable, but many doctors prescribe it readily, and they may not be aware of the especially adverse impact it can have on scleroderma patients.At the very least, I'd make sure the matter was thoroughly discussed and that your doctor is aware of the risks involved. Usually there are alternatives to steroids. (But of course, I'm not a doctor, I have no medical training at all.)See our Scleroderma Lung Treatments page for some ideas. And do the best you can, under trying circumstances.