Washing your Hands in UK Scleroderma Posted January 30, 2016 · Report reply Hi Dimarzio, As it happens, either cold or hot water can set off attacks of Raynaud's. So, when it's an option, try for warm water (even in bathing). And then buy a big supply of packaged hand wipes, and keep them handy in the car, pockets, purses, bathroom...everywhere. It is always worthwhile to avoid an attack of Raynaud's. See Raynaud's Prevention for more tips! I don't have any particular experience with that blood pressure medication.