Scleroderma and Lupus in Sclero Forums (MAIN) Posted June 25, 2016 Hi Alone, Welcome to Sclero Forums. I'm sorry you have confusing symptoms and diagnoses. It's actually fairly common for lupus and scleroderma to occur in overlap, or for either disease to occur in overlap with other diseases. It's common for both diseases to take many years to be diagnosed, and for them to also be mistaken for each other, too. I have multiple autoimmune syndrome (MAS) so I know how confusion can reign supreme as symptoms and bloodwork change. It's also common for relatives of people with autoimmune disease to exhibit antibodies and symptoms of any autoimmune disease, without necessarily ever getting a full-blown version of it. You're not exactly alone in the universe anymore, since millions of people worldwide have autoimmune and connective tissue diseases, and millions are also in a quandary as to their diagnosis -- typically, for many years, as the ailments are so difficult to sort out and diagnose. Plus, even years later, the diagnosis can still be subject to change, or even for the illness to go into remission. Anyway, welcome to the forums. You can relax now, not feel so alone, and let go of the confusion. It's normal for this to be confusing and neither you nor your doctor are doing anything wrong.