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Joelf

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  1. Cleaned endoscopes often contaminated. Many patients may be undergoing endoscopy with contaminated instruments, a pair of new studies suggest. Reuters Health, 04/18/2018. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. Joelf

    Stress.

    Hi Quiltfairy, I'm sorry to hear about your son; it must be very challenging to deal with his misdemeanours and the stress involved cannot be doing your scleroderma symptoms any good. I do hope that you are able to cope with the comments from your family. Best wishes,
  3. Hi Itay, Limited and diffuse scleroderma are two different subsets of the same disease. Diffuse scleroderma is generally distinguished from limited systemic scleroderma by more widespread skin involvement, meaning that the skin thickening may also spread to the upper limbs or torso. Both are systemic, but diffuse tends to progress more quickly, although for some people, the problems caused by limited scleroderma are minor, but for others, limited scleroderma can be life altering and even fatal. Generally though, the prognosis for limited is better and the onset and progression of Limited Scleroderma is usually very slow, and the outlook in general is very good. However, due to the complex nature of the disease it's possible for the diagnosis of scleroderma to change, rather than limited scleroderma progressing into diffuse. Kind regards,
  4. Hi Itay, Welcome to these forums! I'm sorry to hear that you've been recently diagnosed with limited scleroderma and I can understand how worried and concerned you're feeling. I've included a link to our medical page to give you some more information about this. Please note I have no medical training, apart from a now out of date first aid certificate, however, whereas I do appreciate that you're feeling very concerned about taking a strong immunosuppressant such as methotrexate, I would not advise going against your doctors' instructions regarding the medication you take. Alternative therapies are all very well, but in my humble opinion, no substitute for the correct medication. There's no reason why you can't incorporate many healthy, natural things for systemic scleroderma, but you should always get the approval of your medical team before embarking on any new/different therapies or medication. I have limited scleroderma with lung involvement and I was treated with a very strong drug (cyclophosphamide) and have to take an immunosuppressant (azathioprine) and also steroids (prednisolone) and whilst I certainly wasn't ecstatic at the prospect of bombarding my body with powerful medication, it didn't take me long to realise that if I wanted a decent quality of life (or any life at all! ) I would have to take these drugs and basically that was that! That was nine years ago and I'm still going strong and fully intend to continue for many years to come. Kind regards,
  5. Precision medicine using different biological DMARDs based on characteristic phenotypes of peripheral T helper cells in psoriatic arthritis. Strategic treatment in which different bDMARDs were selected according to phenotypic differences in helper T cells showed significantly higher efficacy. PubMed, Rheumatology (Oxford), 04/02/2018. (Also see Psoriasis and Psoriatic Arthritis and Biologic Agents) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. Hi Keevie, Welcome to these forums! I'm sorry to hear that you've been suffering with scleroderma for the last ten years, but pleased to hear that you've got a supportive supervisor. Shelley's given you a useful link to our medical pages on the Causes of Scleroderma, which I hope you'll find helpful and interesting. I do hope that you're being treated by a listed scleroderma expert, as this complex disease does require specialist knowledge and expertise to deal with all it's little idiosyncrasies. Kind regards,
  7. Different profile of cytokine production in patients with systemic sclerosis (SSc) and association with clinical manifestations. SSc patients have a different profile of cytokine production and this was associated with clinical manifestations. PubMed, Immunol Lett, 2018 Mar 27;198:12-16. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  8. Why It Seems Like Everyone Is Always Angry With You. It may be helpful to know that some people seem to have outsize difficulty with reading neutral faces as neutral, even if they are exceptionally accurate at interpreting other facial expressions. New York Times, 04/24/2018. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  9. Low Doses of Etanercept (ETN) Can Be Effective to Maintain Remission in Psoriatic Arthritis (PsA) Patients. The main reasons that hinder the dosing interval increase in ETN in PsA patients are peripheral polyarthritis pattern and exacerbation of cutaneous manifestations. PubMed, J Clin Rheumatol, 2018 Apr;24(3):127-131. (Also see Psoriasis and Psoriatic Arthritis and Biologic Agents) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  10. Serum level of endostatin and digital ulcers (DU) in systemic sclerosis (SSc) patients. Serum levels of endostatin are higher in SSc patients with DUs, especially in those with infected DUs. PubMed, Int Wound J, 03/30/2018. (Also see Digital Ulcers) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  11. The International Scleroderma Network thanks Gilead for their sponsorship support. Posted 05/14/2018.
  12. Concussions May Increase the Risk for Parkinson’s Disease. A traumatic brain injury, even a mild concussion, increases the risk for Parkinson’s disease, a new study reports. New York Times, 04/18/2018. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  13. Joelf

    A ramble. And, hello..

    Hi Heather, Welcome to these forums! I'm sorry to hear that you've been suffering with so many unpleasant and worrying symptoms and I'm sending my best wishes to you. I can understand how frustrating it must be for you to feel that you're getting absolutely nowhere with your doctor/rheumatologist. Unfortunately, there are very few scleroderma experts and I've included a link to our list of them. I'm afraid it may be necessary for you to go out of state to find one to treat you. Failing that, we would recommend that you try and see the best rheumatologist you can. Perhaps if you have a social worker, or similar, they could advise you about claiming disability benefits? I've included a link to our page on Disability Resources, which may give you some more information and ideas. We also have medical pages on Scleroderma and Alternative Therapies, which does have help and advice for many healthy, natural things you can do for systemic scleroderma. Kind regards,
  14. Safety and efficacy of alternate–day corticosteroid treatment (QOD CS) as adjunctive therapy for rheumatoid arthritis (RA) : a comparative study. QOD CS treatment leads to a lower infection rate and less CS dependence than does daily treatment and both RA treatments are equally effective. PubMed, Clin Rheumatol, 03/26/2018. (Also see Treatments for Rheumatoid Arthritis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  15. Incidence of pulmonary hypertension (PH) and determining factors in patients with systemic sclerosis (SSc). It was possible to identify manifest PH in almost 25% of patients using prospective right heart catheterisation during follow-up. PubMed, Eur Respir J, 2018 Apr 4;51(4). (Also see Pulmonary Hypertension Diagnosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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