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Joelf

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Everything posted by Joelf

  1. Quantifying the Effect of Diabetes on Surgical Hand and Forearm Infections. Diabetes exacerbates the burden of surgical upper–extremity infections and higher risk for amputation. PubMed, J Hand Surg Am, 12/11/2017. (Also see Symptoms and Complications of Diabetes) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. Factors associated with the 6–minute walk distance (6MWD) in patients with systemic sclerosis (SSc). During SSc, the 6MWD is independently associated with initial HR and HR variation; suggesting that pulmonary vasculopathy may have a greater impact than parenchymal involvement on functional limitation. PubMed, Arthritis Res Ther, 2017 Dec 15;19(1):279. (Also see Pulmonary Fibrosis Diagnosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  3. Toothpaste ingredient could fight malaria, research shows. Research carried out in part by an artificially–intelligent (AI) ‘robot scientist’ has found that a common ingredient of toothpaste could be developed to fight drug–resistant strains of malaria. Reuters Health, 01/18/2018. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  4. Scoring hypoechogenic areas in one parotid and one submandibular gland increases feasibility of ultrasound in primary Sjögren's syndrome. Ultrasound examination of the parotid and submandibular glands on one side is sufficient to predict classification of patients according to the ACR–EULAR criteria. PubMed, Ann rheumatologist Dis, 12/11/2017. (Also see Diagnosis of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. Raynaud's.

    Hi RKing, I'm sorry to hear that you're suffering with Digital Ulcers; they can be very painful and difficult to heal. Thankfully, I don't suffer with digital ulcers, so can't advise you from my own experience. I've included a link to our medical pages on Treatments for Digital Ulcers, which I hope you'll find helpful and informative. One thing to bear in mind with digital ulcers is that if they are not healing, then they are getting worse. With scleroderma, digital ulcers can lead to amputations. Everything and anything that helps improve circulation may help assist in healing and it is important to consult your doctor/rheumatologist if they're not healing, as it is foolish to attempt to deal with them with home remedies. "Wound Treatment Centres" specialise in the treatment of wounds, so if there's one available in your area, that might perhaps be an option for you. We do have some Pictures of Skin Involvement in Scleroderma, including digital ulcers in our Photo Gallery. Kind regards,
  6. Words of encouragement.

    Hi RKing, Welcome to these forums! Certainly a positive attitude to having scleroderma is beneficial and it is a good idea to obtain as much knowledge about the disease as possible, in order to understand the various treatment options available. As you have surmised, the average rheumatologist finds it difficult to diagnose scleroderma correctly, so we do recommend that our members, if possible, consult a listed scleroderma expert, to ensure that this complicated disease is treated correctly, by someone with the correct knowledge and expertise. I've included a link to our medical pages on Antibodies in Systemic Scleroderma and Raynaud's, to give you some more information. Kind regards,
  7. Do scleroderma patients look young?: Evaluation by using facial imaging system. The severity of wrinkles, texture and pores were significantly lower in SSc patients than control subjects and among them, wrinkles showed better correlation with skin thickness score. PubMed, Drug Discov Ther, 2017;11(6):342-345. (Also see Skin Fibrosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  8. The International Scleroderma Network thanks Genentech for their generous grant to tackle patient education for scleroderma and pulmonary hypertension from 2012 to present. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  9. The International Scleroderma Network thanks Genentech for their sponsorship support. Posted 02/21/2018.
  10. Flu epidemic three times worse than last year at this time. This flu season has already claimed the lives of 30 children, and new research finds it might be spread simply by breathing. NBC Health News, 01/19/2018. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  11. Scleroderma Attitude.

    Hi Quiltfairy, Thanks for your post; it's very true that a positive attitude is so important when dealing with an illness like scleroderma. I'm convinced that it does help with general well being and the effectiveness of treatment programmes. Kind regards,
  12. Rheumatic diseases are associated with a higher risk of dementia: A nation–wide, population–based, case–control study. In this population–based case–control study, we found that patients with rheumatic diseases are significantly associated with a higher risk of dementia. PubMed, Int J rheumatologist Dis, 12/15/2017. (Also see Systemic Autoimmune Rheumatic Diseases) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  13. Anyone have similar results?

    Hi JDPrater, Welcome to these forums to you and your wife! I'm sorry you have concerns about scleroderma and your wife's test results. I can understand how worrying these test results appear to be, but your doctor is going to have to explain the test results as they interpret them in your particular case. Please understand that I have no medical training, apart from a now out of date first aid certificate, but I would reiterate the advice we always give about positive blood tests; although they help in the diagnostic process, they are by no means the be all and end all of a diagnosis, as scleroderma is extremely complex to diagnose and it is possible to have positive blood tests and yet never go on to develop the full blown disease and vice versa, as many of our members can testify. Far more important are the clinical signs and symptoms of the disease. I'm afraid that the journey to a scleroderma diagnosis can be long and frustrating, not least because the disease presents itself in so many different ways and affects all sufferers differently. It's likely that when you have your next rheumatologists' appointment, you may not be any further forward in obtaining a diagnosis. We do recommend that our members, if possible, consult a listed scleroderma expert, to ensure that this complicated disease is treated correctly, by someone with the correct knowledge and expertise. I've included a link to our medical page on Antibodies in Systemic Scleroderma, which I hope you'll find helpful and informative. Kind regards,
  14. Skin mapping for the classification of generalized morphea. Symmetric and isomorphic subsets possess distinctive demographic and clinical features, suggesting they more accurately define the phenotype of generalized morphea. PubMed, J Am Acad Dermatol, 2018 Feb;78(2):351-357. (Also see Morphea) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  15. Update) Sara P: CREST Syndrome I am still doing well. I’ve been stable on the PAH meds, Opsumit and ADCIRCA....... Posted 02/16/2018. There are over 1,000 patient and caregiver stories on the main Sclero.org site.Over 300 of these stories are featured in the Voices of Scleroderma book series.
  16. Birth Control Pills May Help Prevent Some Cancers. In a new study published in JAMA Oncology, researchers explore how oral contraceptives, which affect women’s hormone levels to prevent pregnancy, affect cancer risk. Time Healthland, 01/18/218. (Also see Cancer) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  17. The risk of malignancy and its incidence in early rheumatoid arthritis (RA) patients treated with biologic DMARDs. In early RA patients, bDMARD use decreases the overall risk of developing malignancies; however, it does not affect the risk of developing hematologic malignancies. PubMed, Arthritis Res Ther, 2017 Dec 15;19(1):277. (Also see DMARDs and Treatments for Rheumatoid Arthritis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  18. Titer levels

    Hi Ana, Welcome to these forums! I'm afraid I have no personal experience with titer levels decreasing (or increasing, for that matter. ) However, I've included links to some previous threads dealing with the subject, which I hope will be helpful to you. High Anti-Centromere Antibodies, but Zero symptoms. Centromere Antibodies? Clarification for interpreting ANA and scl 70 scores. Positive ANA, SCL-70 but no symptoms - are other people in the same situation? The subject of positive antibodies and blood tests does arise very frequently on these forums and I would reiterate the advice we always give about them; although they help in the diagnostic process, they are by no means the be all and end all of a diagnosis, as scleroderma is extremely complex to diagnose and it is possible to have positive blood tests and yet never go on to develop the full blown disease and vice versa, as many of our members can testify. Far more important are the clinical signs and symptoms of the disease. The best person to advise you is a listed scleroderma expert. Kind regards,
  19. Disease staging and sub setting of interstitial lung disease associated with systemic sclerosis (SSc–ILD): impact on therapy. In the management of SSc–ILD, a multidisciplinary team approach which integrates physiology and radiology with the patient at the centre of the process is crucial for effective management and provision of the best outcomes. PubMed, Expert Rev Clin Immunol, 01/10/2018. (Also see Treatments for Pulmonary Fibrosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  20. Reproductive Factors in Women Tied to Heart Disease and Stroke Risk. Several female reproductive factors are associated with an increased risk for heart disease and stroke, British researchers report. New York Times, 01/18/2018. (Also see Cardiac (Heart) Involvement) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  21. The International Scleroderma Network thanks Gilead for sponsorship support to tackle scleroderma and pulmonary hypertension from 2011 to present. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  22. The International Scleroderma Network thanks Gilead for their sponsorship support. Posted 02/14/2018.
  23. Scleroderma diagnosis forthcoming?

    Hi Rentalguy1, It does sound as if your rheumatologist is taking the initiative and dealing with you as well as he can, so I hope that he'll be able to advise and help you. I've included a link to our medical pages on Causes of Scleroderma, which I hope you'll find helpful and informative. Kind regards,
  24. Hi Mnmom, Thanks so much for updating us and I’m very pleased to hear that you’ve found a doctor in whom you can have confidence. I do hope that Dr Torok will be able to help and advise you and that your daughter will do well under his treatment. Kind regards,
  25. Endothelial dysfunction in early systemic lupus erythematosus patients and controls without previous cardiovascular events. A high rate of endothelial dysfunction and vascular stiffness occurs in early lupus patients without cardiovascular risk factors and disease. PubMed, Arthritis Care Res (Hoboken), 12/15/2017. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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