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Joelf

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Everything posted by Joelf

  1. Explainer: How worried should we be about reports of blood clots and AstraZeneca's vaccine? Europe's drug watchdog is reviewing a small number of reports of bleeding, blood clots and low platelet counts in people who have received AstraZeneca's coronavirus vaccine. Reuters Health, 03/17/2021. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. Neurological Involvement in Patients With Primary Sjögren's Syndrome (pSS). Patients with pSS with a high titer of anti-Sjögren's syndrome type A and low presence of anti-Sjögren's syndrome type B antibodies might have a relatively high risk of developing neurological involvement. PubMed, J Clin Rheumatol, 2021 Mar 1;27(2):50-55. (Also see Symptoms and Complications of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  3. Cardiovascular Autonomic Control, Sleep and Health Related Quality of Life in Systemic Sclerosis (SSc). Dysautonomia and chronic pain showed a severe impact on sleep quality and disability with a consequent worsening of depressive symptom in our cohort of SSc patients. PubMed, Int J Environ Res Public Health, 2021 Feb 25;18(5):2276. (Also see Brain (Cerebral) Involvement and Sleep Disorders) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  4. Advanced Cancers Are Emerging, Doctors Warn, Citing Pandemic Drop in Screenings. Appointments for mammograms and other tests to detect potential cancers were canceled during lockdowns, possibly leading to undiagnosed malignancies. New York Times, 03/17/2021. (Also see Cancer) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. The Treatment of Lung Involvement in Systemic Sclerosis (SSc). Treatment planning and intensity are guided by the disease severity and risk of progression and herein, recent advances in SSc-interstitial lung disease treatment will be explored. PubMed, Pharmaceuticals (Basel), 2021 Feb 13;14(2):154. (Also see Treatments for Pulmonary Fibrosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. The Pandemic and the Limits of Science. Even now, medicine has a better grasp of how to prevent coronavirus infection — masks, social distancing, vaccination — than how to treat it. New York Times, 03/16/2021. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  7. Application of artificial intelligence (AI) in diagnosis of osteoporosis using medical images: a systematic review and meta-analysis. The application of AI-based systems in osteoporosis diagnosis needs to be further confirmed by more prospective studies in multi-centers including more random samples from complete patient types. PubMed, Osteoporos Int, 02/27/2021. (Also see Osteoporosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  8. Case Report: Novel case of a scleroderma-mimicking syndrome associated with gastrointestinal stromal tumour (GIST). While there have been previous descriptions of paraneoplastic fibrotic disorders, this is the first description of a scleroderma mimic in the setting of a GIST. PubMed, BMJ Case Rep. (Also see Gastrointestinal Involvement) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  9. New diabetes guidelines lower screening age to 35 for some adults. Screening for Type 2 diabetes and prediabetes should start at age 35 for people who are considered overweight, instead of the currently recommended age 40. NBC Health News, 03/16/2021. (Also see Prevention of Diabetes) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  10. Distribution of IgG subclass anti-nuclear antibodies (ANAs) in systemic lupus erythematosus (SLE). We demonstrated that the ANA IgG subclasses were diagnostic tools in SLE patients and therefore, an altered ANA IgG subclass distribution might be a risk factor influencing the inflammatory process in SLE. PubMed, Lupus, 2021 Feb 23;961203321995242. (Also see Antibodies in Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  11. Prevalence of Barrett's Esophagus (BE) in Female Patients With Scleroderma (SSc). The high prevalence and incidence of dysplasia found suggest that women with SSc should be included in the screening recommendations for BE. PubMed, Am J Gastroenterol, 2021 Mar 1;116(3):517-521. (Also see Esophageal (Throat) Involvement) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  12. How the pandemic has changed our bodies. Whether or not you've been lucky enough to dodge the coronavirus for the last year, the global pandemic still could be taking a toll on your body, from your brain to your skin. NBC Health News, 03/13/2021. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  13. Utility of lymphocyte phenotype profile to differentiate primary Sjögren syndrome (pSS) from Sicca syndrome. Patients with pSS show a profound imbalance in the distribution of circulating T and B lymphocytes subsets. PubMed, Rheumatology (Oxford), 2021 Feb 23;keab170. (Also see Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  14. Self-management interventions in systemic sclerosis: A systematic review. Future research in systemic sclerosis should include key self-management outcomes in larger, more rigorously designed studies to allow for comparisons across studies and to advance the science of self-management. PubMed, Res Nurs Health, 2021 Apr;44(2):376-392. (Also see Arthritis Treatments - General) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  15. You Should Still Get Vaccinated Even If You've Already Had COVID-19, Study Shows. In one of the first large studies exploring immunity from natural infection with COVID-19, researchers in Denmark found some surprising trends – including evidence that even those who previously contracted the disease should still get vaccinated. Time Healthland, 03/17/2021. (Also see Vaccinations) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  16. Fibromyalgia (FM) and obesity: A comprehensive systematic review and meta-analysis. Available data support a potential interplay between obesity and FM-related symptoms, therefore weight management should be encouraged in patients with FM. PubMed, Semin Arthritis rheumatologist, 2021 Mar 3;51(2):409-424. (Also see Treatments for Fibromyalgia) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles
  17. Congruent microbiome signatures in fibrosis-prone autoimmune diseases: IgG4-related disease and systemic sclerosis. These results provide an initial characterization of gut microbiome ecology in fibrosis-prone IgG4-RD and SSc and reveal microbial functions that offer insights into the pathophysiology of these rare diseases. PubMed, Genome Med, 2021 Feb 28;13(1):35. (Also see Gastrointestinal Involvement) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles
  18. Covid-19: Cambridge scientists study DNA for long Covid clues. Scientists are investigating whether genetics impact on recovery from coronavirus, as part of research into "long Covid". BBC Health News, 03/18/2021. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  19. Modifiable Psychological Factors Affecting Functioning in Fibromyalgia. Our findings suggest that pain catastrophizing appears to be an especially important variable contributing to reduced functioning and so catastrophizing-reducing treatments (e.g., cognitive behavioral therapy) are likely to have direct, beneficial impacts on functioning. PubMed, J Clin Med, 2021 Feb 17;10(4):803. (Also see Fibromyalgia) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  20. Hi Margaret, What a lovely idea! Come on everyone; let's hear how you've all been doing. Kind regards,
  21. Hi Margaret, That's interesting and what a good thing that Gareth's doctor has found a satisfactory way to deal with his Oesophageal dismotility. So many scleroderma sufferers seem to have GI issues to deal with, which can make their lives so miserable. Kind regards,
  22. Natural Killer (NK) Cells: Potential Biomarkers and Therapeutic Target in Autoimmune Diseases? Because of its role in modulating the immune-mediated pathology, NK subpopulation could represent a potential marker for disease activity and target for therapeutic intervention. PubMed, Front Immunol, 2021 Feb 19;12:616853. (Also see Natural Killer Cells) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  23. Progression of gastrointestinal (GI) symptoms over time in patients with systemic sclerosis (SSc). Patients with SSc generally demonstrate longitudinal stability or improvement in their GI symptoms, but a subset of patients experience worsening of GI symptoms and negative impacts on GI-related quality of life. PubMed, Rheumatol Int, 02/25/2021. (Also see Gastrointestinal Involvement) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  24. Eating breakfast before 8:30am can reduce your risk of developing type 2 diabetes, study finds. Eating breakfast before 8:30 in the morning can lower your insulin resistance, reducing your risk of developing type 2 diabetes, a study found. Mail Online, 03/18/2021. (Also see Prevention of Diabetes) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  25. Evidence for the efficacy of Tai Chi for treating rheumatoid arthritis: an overview of systematic reviews. The findings suggest that clinical improvement was achieved, although not statistically significant with regard to pain and disease pattern, as assessed using the American College of Rheumatology 20% (ACR20) measurement. PubMed, Sao Paulo Med J, 2021 Mar 3;S1516-31802021005006201. (Also see Treatments for Rheumatoid Arthritis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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