CraigR

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About CraigR

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    Escondido (near San Diego), Ca
  1. Unfortunately, this is a very difficult disease to diagnose, so do not jump to conclusions. I am not a medical professional, but there is often a wait and see attititude. Even with diffuse sclero, the outcomes are very different. Craig
  2. Sjögren’s syndrome, the old and the new. An extensive review the postulated aetiologies, pathogenesis and new insights related to Sjögren’s syndrome. Best Pract Res Clin Rheumatol. 2012 Feb;26(1):105-17. (Also see: Sjogren's) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  3. After my appointment on 7-10 I had more bloodwork that was still negative for muscle enzyme and high sed and CRP rates, though there was improvement. I am setting up an appointment with a neurologist. There has been improvement, but too slow for me! For a quite a while I've suspected some sort of neurological damage from cancer chemotherapy, since my balance was so bad that I required a cane, in spite of a great deal of exercise So we will see. Craig
  4. Thanks for the info. I see my rheumatologist tomorrow and this is good for discussion. I am slowly improving (but not nearly fast enough...) I don't know that a nerve disorder such as sciatica would cause high inflammation (my only positive tests were a very high SED rate and high CRP), which points more toward MS or MG. The symptoms sound much like MG, but were legs only. Oddly, I have had attacks in my upper body (to the point of pain making breathing difficult), but never upper and lower body at the same time. Craig
  5. Intensity and Duration of Anticoagulation Therapy in Antiphospholipid Syndrome. A recent consensus document recommends warfarin to an INR range of 2.0 to 3.0 for patients with a first venous thromboembolic event. Higher anticoagulation intensity is recommended for patients presenting with arterial events. Semin Thromb Hemost. 2012 Mar 30. (Also see: Antiphospholipid Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  6. I've developed a severe muscle disorder in my legs over the past 2 months. Following a cold with a persistent cough, I developed severe back pain that soon became great leg pain - especially when moving then (little pain when resting). My rheumatologist suspected myositis, but muscle enzyme tests came back normal. I've had myalgia/myositis issues in the past, but of the upper body. At the worst, It took heavy pain relievers and 80 mg of prednisone a day just to make it possible to get out of a chair. All tests were normal except ESR ( erythrocyte sedimentation rate) and CRP (C-reactive protein) which were highly elevated. My rheumatologist thinks the muscle enzyme test may have been falsely negative due to taking prednisone. I have reduced medication since that time. The critical stage has passed, but I require a walker to get around, due to weakness and ongoing inflammation and it doesn't seem to be improving. I would like to find out who might be an expert on such matters. Light exercise does not seem helpful since it increases pain. My history is slow-onset sclero with Sjogren's and pulmonary hypertension. My latest autoimmine panel oddly did not show any sclero antibodies, but showed both Sjogren's antibodies. Anybody had anything similar? Craig
  7. Short-term and long-term consequences and concerns regarding valid assessment of vitamin D deficiency: comparison of recent food supplementation and clinical guidance reports. Healthcare providers should formulate their own opinions with respect to vitamin D as it pertains to the care of their patient. PubMed. Curr Opin Clin Nutr Metab Care. 2011 Sep 19. (Also see: Supplement Guide for Scleroderma) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  8. Infectious diseases and autoimmunity. Besides genetic predisposition to autoimmunity, viral and bacterial infections are known to be involved in the initiation and promotion of autoimmune diseases. PubMed. Journal of Infection in Developing Countries. 2011 Oct 13;5(10):679-87. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  9. When I have had thIs, I bandage the finger and pad it heavily so that it does not strike anything painfully. Long ago I had a doctor (family practice) who would anesthetize the finger and cut out the calcium deposit, especially when especially painful (such as up against a nerve). Craig
  10. A current perspective on Sjögren's syndrome. Recent developments are unlocking the mystery of the disease process as well as contributing to our ability to define, diagnose, and develop new treatment modalities for patients with this complex disorder. PubMed. J Calif Dent Assoc. 2011 Sep;39(9). (Also see: Sjogren's Syndrome ) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  11. Autoimmune disease and gender: Plausible mechanisms for the female predominance of autoimmunity. Hormonal changes as well as the genetic factors that could explain why women are more prone to develop autoimmune diseases are reviewed. Journal of Autoimmunity, 2011 Nov 11. (Also see: Autoimmunity) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  12. Liver complications in celiac disease. Information regarding liver disorders that may be found in association with celiac disease and the effect of the treatment of celiac disease on these disorders. Hepatitis Monthly, 2011 May 1;11(5):333-341. (Also see: Celiac Disease) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  13. Antiphospholipid syndrome in obstetrics. The clinical hallmarks of this syndrome are thrombosis and poor obstetric outcomes, including miscarriages, fetal loss and severe pre-eclampsia. Best Pract Res Clin Obstet Gynaecol. 2011 Nov 10. (Also see: Antiphospholipid Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  14. Aluminum as an adjuvant in Crohn's disease induction. Aluminum is a potential factor for the induction of inflammation in Crohn's disease. PubMed. Lupus. 2012;21(2):231-8. (Also see: Inflammatory Bowel Disease) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)
  15. Vaccine model of antiphospholipid syndrome induced by tetanus vaccine. Successful induction of antiphospholipid syndrome (APS) in two different non-autoimmune prone mouse strains, was achieved by tetanus toxoid hyperimmunization. PubMed. Lupus. 2012;21(2):195-202. (Also see: Antiphospholipid Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Craig Roothoff ISN Assistant News Guide International Scleroderma Network(ISN)