I'm new here. I'm 28 years old and received my lab results a month and a half ago. Positive ANA and Anti-Scl-70 (4.4). I keep reading that Anti-Scl-70= systemic scleroderma=poor prognosis/organ involvement/rapid thickening of the skin. My rheumatologist can't give me any clear-cut answers to any of my questions. He says autoimmune diseases are tricky to diagnose and we have to "wait and see" how I respond to medication (Plaquenil) and also get more tests done. The waiting and seeing is the part I'm struggling with. Actually, I'm struggling with the whole thing- the actual symptoms, the anxiety of not knowing, the prospect of not being able to live the life I want to. I also don't even have a diagnosis yet. Or maybe I do? I'm confused about what the positive Anti-Scl-70 means. Is it always indicative of systemic scleroderma? How likely are false positives?
I'm new here too. I tested positive for ANA and Anti-Scl 70 about a month and a half ago. I'm 28 years old. My symptoms started a couple years ago, but they were vague and varied and would come and go (inflamed eyelids/dry eye/eye sensitivity, joint pain, especially the toes, fatigue, difficulty breathing, excessive sweating, stomach bloating) Anyway, I've read the same thing, that the positive Anti-Scl 70=poor prognosis. My rheumatologist explained that the prognosis usually depends on how far along your disease has progressed when you begin treatment. He told me that based on my symptoms he feels I'm still in the early stages of the disease. It sounds like you are too. I don't know if that helps at all.