ANA positive, Anticentromere positive, but no symptoms in Sclero Forums (MAIN) Posted November 8, 2019 Hi Jacob, I am a 23 year old female with the same antibodies and asymptomatic! I figured all this out about 10 months ago, and I'm still fine. Since your GERD was already present for many years, I doubt it relates to the antibodies. My mom has terrible GERD - so that can be a genetic thing. I also run a lot, eat really healthy, and what not. I would suggest we stay proactive with our health and not worry too much(even though it can be hard) because we still have a nice long life ahead! I read alot on ACA --- it can occur in individuals with Lupus or other diseases - and sometimes nothing can ever arise from them. Hope all is well!