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  1. I have had diffuse scleroderma for 19 months and I was wondering at what point will my skin on my arms stop irritating me.
  2. I was diagnosed with Diffuse Scleroderma with positive polymerase III and I am needing some info on anyone taking combination therapy. I have been on cellcept for 9 months which seems to have helped some but I was put on Rituxan about 7 months ago. I have had 3 infusions and I am receiving my 4th Sept 3. My infusions are in a series of 2 every 6 months. I started to see a specialist and he wants me on actemra instead of Rituxin. Has anyone had improvements with Rituxan or Actemra? I feel cellcept has had the most effect. I know everyone is different and reacts different
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