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Treatments of osteoporosis increase bone material strength index (BMSi) in patients with low bone mass. In patients at increased fracture risk, antiresorptive treatments induced BMD-independent increases in BMSi values, the magnitude of which depended on pretreatment values. PubMed, Osteoporos Int, 04/08/2020. (Also see Osteoporosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.