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Understanding the Light and Dark Sides to Anxiety with Chronic Illness. Anxiety can be exacerbated or caused by the experience of constant pain blended with feeling exhausted and unwell. Scleroderma News, 03/20/2018. (Also see Anxiety and Attitude) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.