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Long-standing morphea and the risk of squamous cell carcinoma of the skin (cSCC). Fibrosis, inflammation and chronic ulcerations may eventually promote skin neoplasms; morphea is therefore a rare but established risk factor for cSCC. PubMed, J Dtsch Dermatol Ges, 05/04/2020. (Also see Causes of Morphea) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.