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Found 6 results

  1. The IL-1 family of cytokines. Do they have a role in scleroderma fibrosis? Recent analyses of the IL-1 family of cytokines have demonstrated that many of them play a role in skin inflammation and fibrosis and their corresponding antagonists (IL-1RA and IL-36RA) can abrogate this pathology. PubMed, Immunol Lett, 12/04/2017. (Also see Interleukins) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. Inflammasome lights up in systemic sclerosis. The innate immune system and small RNA molecules known as microRNA are key factors in the development of scleroderma. BioMed Central, Arthritis Res Ther, 2017; 19: 205. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  3. IRF7 gene expression profile and methylation of its promoter region in patients with systemic sclerosis (SSc). Hypomethylation of the IRF7 promoter might play a role in SSc pathogenesis, probably through promoting the IRF7 expression in peripheral blood mononuclear cells of patients with SSc. PubMed, Int J rheumatologist Dis, 09/26/2017. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  4. Cytokine signature associated with disease severity in chronic fatigue syndrome patients (CFS). The physicians explored the role of cytokine in CFS and they explained that most of the cytokines were proinflammatory and probably contributed to many of the symptoms of CFS. PubMed, Proc Natl Acad Sci U S A, 2017 Aug 22;114(34):E7150-E7158. (Also see Chronic Fatigue Syndrome and Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. Th–17 cytokines and interstitial lung involvement in systemic sclerosis (SSc). In diffuse SSc patients our results show a clear link between Th–17 cytokines measured both in exhaled breath condensate and in serum with interstitial lung involvement. PubMed, J Breath Re, 2016 Nov 21;10(4):046013. (Also see Cytokines and Pulmonary Fibrosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. Association Between Corrected QT (QTc) Interval and Inflammatory Cytokines in Rheumatoid Arthritis (RA). A lower inflammatory burden may protect against QTc prolongation in patients with RA. PubMed, J Rheumatol, 01/15/2015. (Also see: Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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