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Found 9 results

  1. Gastric Juice Expression of Th-17 and T-Reg Related Cytokines in Scleroderma Esophageal Involvement. This is the first report of cytokines measurement in gastric juice of patients with SSc. PubMed, Cells, 2020 Sep 16;9(9):E2106. (Also see Esophageal (Throat) Involvement and Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. The Roles of IL-1 Family Cytokines in the Pathogenesis of Systemic Sclerosis (SSc). Here, we aim to give a brief overview of IL-1 family cytokines and discuss their pivotal roles in the pathogenesis of SSc. PubMed, Front Immunol, 2019 Sep 13;10:2025. (Also see Interleukins) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  3. CCL3, IL-7, IL-13 and IFNγ transcripts are increased in skin's biopsy of systemic sclerosis (SSc). These molecules are involved in the pathogenesis of SSc, and how their interactions occur should be the subject of further studies. PubMed, Exp Dermatol, 06/04/2019. (Also see Skin Fibrosis and Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  4. Type I interferon dysregulation in Systemic Sclerosis. Here we describe the evidence of Type I IFN dysregulation in SSc, revealed predominately by genetics and gene expression profiling. PubMed, Cytokine, 01/23/2019. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. A TNFSF13B functional variant is not involved in systemic sclerosis (SSc) and giant cell arteritis (GCA) susceptibility. Our data suggest that the TNFSF13B functional variant does not contribute to the genetic network underlying GCA and SSc. PubMed, PLoS One, 2018 Dec 26;13(12):e0209343. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. Analysis of serum macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase in systemic sclerosis (SSc). Although not significantly linked to specific clinical parameters, serum MIF was significantly higher in SSc patients than in healthy controls and systemic lupus erythematosus patients. PubMed, Clin Transl Immunology, 2018 Dec 6;7(12):e1042. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  7. Statins Inhibit Cytokines in a Dose–Dependent Response in Patients with Systemic Sclerosis (SSc). Statins, particularly simvastatin, appear to have an immunosuppressive effect in reducing all cytokine secretion levels from peripheral blood mononuclear cells of SSc in a dose–dependent manner. PubMed, Inflammation, 10/04/2018. (Also see Statins and Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  8. Different profile of cytokine production in patients with systemic sclerosis (SSc) and association with clinical manifestations. SSc patients have a different profile of cytokine production and this was associated with clinical manifestations. PubMed, Immunol Lett, 2018 Mar 27;198:12-16. (Also see Cytokines) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  9. The IL-1 family of cytokines. Do they have a role in scleroderma fibrosis? Recent analyses of the IL-1 family of cytokines have demonstrated that many of them play a role in skin inflammation and fibrosis and their corresponding antagonists (IL-1RA and IL-36RA) can abrogate this pathology. PubMed, Immunol Lett, 12/04/2017. (Also see Interleukins) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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