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Found 13 results

  1. Large-scale characterization of systemic sclerosis serum protein profile: Comparison to peripheral blood cell transcriptome and correlations with skin/lung fibrosis. Diffuse scleroderma has a distinct serum protein profile with prominent dysregulation of proteins related to fibrosis and immune cell adhesion/diapedesis. PubMed, Arthritis Rheumatol, 11/01/2020. (Also see Diffuse Scleroderma and Skin Fibrosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. I'm trying the autoimmune protocol (AIP) diet in a desperate attempt to outwit very rapidly progressing diffuse Scleroderma and myositis. I was very fit two years ago,and only had Sjogren's symptoms this time last year, plus mild Raynaud's. It is my only hope. I'm having a scary time with huge changes each week, struggling with walking, eating, much pain etc. I haven't yet been started on any medication.Can anyone suggest what medication can help please? Also does anyone find the AIP or other diet helps? Thanks for any feedback.
  3. Hello, I really hope that you guys can help me a bit with following problem: One year ago I went to my rheumatologist because I had stiffness in my fingers and pain (in the morning and also in the night). It always gets worse in summer when It gets warmer (it is somehow also linked to sweating). There were days when I could barely write because my hands felt puffy, started to sweat a lot and were extremely stiff. My doctor found out that I have scl 70 antibodies, my ANAs have been always negative (I do regular check ups), no rheumatoid factor, all other Blood values
  4. Estradiol (E2) levels are elevated in older men with diffuse cutaneous SSc and are associated with decreased survival. Our study expands on previous work implicating E2 in dermal fibrosis in SSc and associates E2 levels with internal organ involvement and survival. PubMed, Arthritis Res Ther, 2019 Apr 2;21(1):85. (Also see Diffuse Scleroderma) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis. Skin gene expression of biomarkers may provide guidance in decision–making about which patients should be considered for aggressive therapies and/or for clinical trials. PubMed, Arthritis Rheumatol, 2018 Jun;70(6):912-919. (Also see Diffuse Scleroderma and Skin Fibrosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. Disability, fatigue, pain and their associates in early diffuse cutaneous systemic sclerosis (dcSSc): the European Scleroderma Observational Study. The European Scleroderma Observational Study highlights the burden of disability in early dcSSc, with high levels of disability and fatigue, associating with the degree of skin thickening (mRSS). PubMed, Rheumatology (Oxford), 11/30/2017. (Also see Diffuse Scleroderma) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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