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Linear scleroderma "en coup de sabre" with extensive brain involvement-Clinicopathologic correlations and response to anti-Interleukin-6 therapy. The interleukin-6 (IL-6) receptor inhibitor tocilizumab was used and the patient improved dramatically, likely reflecting the drug's effect on the replenishment of endothelial progenitor cells. PubMed, Orphanet J Rare Dis, 2019 May 16;14(1):110. (Also see En Coup de Sabre) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.

Association between leptin and IL-6 concentrations with cardiovascular risk (CVR) in patients with rheumatoid arthritis. There is a positive association between CVR and serum leptin concentrations and it is also significantly associated with traditional and non–traditional risk factors. PubMed, Clin Rheumatol, 11/03/2017. (Also see Symptoms and Complications of Rheumatoid Arthritis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.