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Characteristics and Outcomes of Patients With Systemic Sclerosis (Scleroderma) Requiring Renal Replacement Therapy in Europe. Patients with scleroderma had a higher rate of recovery from renal replacement therapy dependence than controls. PubMed, Am J Kidney Dis, 08/16/2018. (Also see Kidney (Renal) Dialysis and Transplant) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.