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  1. Risk factors associated with adverse pregnancy outcomes (APOs) in patients with new–onset systemic lupus erythematosus (SLE) during pregnancy. New onset SLE during pregnancy increased the risk for multiple APOs. PubMed, Lupus, 2021 Jan 6;961203320980531. (Also see Symptoms and Complications of Lupus and Pregnancy and Autoimmunity) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. Case report: Synchronous Volvulus of the Transverse Colon and Cecum Associated with Scleroderma and Lupus. To our knowledge, this is the first reported case of synchronous double volvulus of the transverse colon and cecum. PubMed, Radiol Case Rep. (Also see Bowel Dysfunction and Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  3. The dermatoscopic spectrum of cutaneous lupus erythematosus (CLE): a retrospective analysis by clinical subtype with clinicopathological correlation. Depending on CLE subtype, distinct dermatoscopic patterns are recognized. PubMed, Dermatol Ther, 11/09/2020. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  4. Mortality in patients with systemic lupus erythematosus (SLE) and neuropsychiatric (NP) involvement: A retrospective analysis from a tertiary referral center in the Netherlands. Mortality was increased in both major NPSLE and minor/non-NPSLE patients in comparison with the general population. PubMed, Lupus, 2020 Oct 20;961203320963815. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. Blood–brain barrier (BBB) leakage in systemic lupus erythematosus (SLE) is associated with gray matter loss and cognitive impairment. Our findings provide evidence for a link between extensive BBB leakage and changes in both brain structure and cognitive function in patients with SLE. PubMed, Ann rheumatologist Dis, 10/01/2020. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. Systemic lupus erythematosus; stroke and myocardial infarction (MI) risk: a systematic review and meta-analysis. Overall, patients with SLE were identified to have a twofold to threefold higher risk of stroke and MI. PubMed, Clin Lab, RMD Open, 2020 Sep;6(2):e001247. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  7. Prevalence of antiphospholipid antibodies in patients with overt myocardial dysfunction in systemic lupus erythematosus. A case-control study. This study did not find any significant association of anti-phospholipid antibodies with overt myocardial dysfunction in patients of SLE. PubMed, Lupus, 2020 Aug 4;961203320947784. (Also see Symptoms and Complications of Lupus and Antiphospholipid Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  8. Cachexia in Systemic Lupus Erythematosus (SLE): Risk Factors and Relation to Disease Activity and Damage. Cachexia is an underrecognized syndrome in patients with SLE and SLE patients with intermittent cachexia have the highest risk of future organ damage. PubMed, Arthritis Care Res (Hoboken), 08/02/2020. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  9. Cervical Cancer Screening in Women with Systemic Lupus Erythematosus (SLE). Patients with SLE are at higher risk of abnormal cervical screening test results than controls, supporting the need for regular screening. PubMed, Arthritis Care Res (Hoboken), 08/16/2020. (Also see Cancer and Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  10. Left Ventricular (LV) Systolic Function in Patients With Systemic Lupus Erythematosus (SLE) and Its Association With Cardiovascular Events. In patients with SLE, LV systolic function as measured by LV global longitudinal strain is significantly impaired and associated with cardiovascular events. PubMed, J Am Soc Echocardiogr, 2020 Jul 1;S0894-7317(20)30230-3. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  11. A Population-based Study of Risk Factors for Heart Failure in Pediatric and Adult-onset Systemic Lupus Erythematosus (SLE). Hypertension remains an important traditional cardiovascular risk factor across all ages and should be managed aggressively even in younger patients with SLE. Seminars in Arthritis and Rheumatism, 05/03/2020. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  12. Effect of early eradication therapy on systemic lupus erythematosus (SLE) risk in patients with Helicobacter pylori (HP) infection: a nationwide population-based cohort study. Early HP eradication could significantly reduce SLE risk, especially in the first three-year follow-up. PubMed, Lupus, 2020 May 7:961203320923393. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  13. Interleukin-34 as a marker for subclinical proliferative lupus nephritis (LN). Serum IL-34 may be used as a surrogate marker for early renal affection in silent LN, especially the proliferative type. Sage Journals, Lupus, 04/01/2020. (Also see Symptoms and Complications of Lupus and Interleukins) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  14. Retinal Complications in Patients with Systemic Lupus Erythematosus Treated with Antimalarial Drugs. Just over 5% of patients developed antimalarial retinal complications, over an average of 12.8 years, but no cases were detected in the first 5 years of therapy. PubMed, J Rheumatol, 2020 Apr;47(4):553-556. (Also see Symptoms and Complications of Lupus and DMARDs) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  15. Profiling of non-criteria antiphospholipid antibodies in patients with systemic lupus erythematosus (SLE): differentiation of thrombotic SLE patients and risk of recurrence of thrombosis. Profiling of antiphospholipid antibodies by line immunoassay can differentiate SLE patients with thrombosis from SLE patients without thrombosis. PubMed, Lupus, 2020 Mar 4:961203320909952. (Also see Antibodies in Lupus and Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  16. Construction of a Frailty Index (FI) as a Novel Health Measure in Systemic Lupus Erythematosus (SLE). The SLICC-FI may be a useful tool for identifying patients with SLE who are most vulnerable to adverse outcomes. PubMed, J Rheumatol, 2020 Jan;47(1):72-81. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  17. Systemic lupus erythematosus (SLE) is a risk factor for atrial fibrillation (AF): a nationwide, population-based study. Development of AF in patients with SLE was associated with increased mortality. PubMed, Clin Exp Rheumatol, 2019 Nov-Dec;37(6):1019-1025. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  18. The Impact of Systemic Lupus Erythematosus (SLE) on the Risk of Newly Diagnosed Hip Fracture. A General Population-Based Study. Patients with newly diagnosed SLE have a 62% increased risk of hip fractures compared to non-SLE individuals. PubMed, Arthritis Care Res (Hoboken), 11/23/2019. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  19. Different patterns of cerebral perfusion in systemic lupus erythematosus (SLE) patients with and without neuropsychiatric (NP) manifestations. Cerebral blood flow measured by noninvasive three-dimensional arterial spin labeling could be a useful biomarker for the diagnosis and disease monitoring of NPSLE and non-NPSLE patients. PubMed, Hum Brain Mapp, 10/24/2019. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  20. Biomarkers associating endothelial Dysregulation in pediatric-onset systemic lupus erythematous (pSLE). Endothelial dysregulation associating proteins seems to be potent biomarkers for pSLE activity as well as organ involvement in pSLE patients. PubMed, Pediatr Rheumatol Online J, 2019 Oct 24;17(1):69. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  21. Dysregulated Fc gamma receptor IIa-induced cytokine production in dendritic cells (DCs) of lupus nephritis patients. We identified that DCs of lupus nephritis patients show increased Fcγ R-induced IL-1β production, which is another important cytokine that promotes kidney inflammation. PubMed, Clin Exp Immunol, 09/11/2019. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  22. Heart failure (HF) risk in systemic lupus erythematosus (SLE) compared to diabetes mellitus (DM) and general medicaid patients. Further investigation into the biologic mechanism of HF among SLE compared to non-SLE and DM patients may shed light on the findings of this study. PubMed, Semin Arthritis rheumatologist, 06/11/2019. (Also see Symptoms and Complications of Lupus and Symptoms and Complications of Diabetes) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  23. Complement alternative pathway activation associated with pulmonary hypertension in lupus nephritis patients. Activation of the complement alternative pathway may be involved in the pathogenesis of pulmonary hypertension in lupus nephritis. PubMed, Lupus, 2019 Jul 11:961203319860192. (Also see Symptoms and Complications of Lupus and Pulmonary Hypertension) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  24. Septic shock among patients with systemic lupus erythematosus (SLE): short and long–term outcome. Analysis of a French nationwide database. Septic shock is a frequent and severe complication among SLE patients even if it is not associated with more healthcare use than another episode of same severity. PubMed, J Infect, 04/08/2019. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. 
  25. Metabolic syndrome (MetS) in patients with systemic lupus erythematosus: Association with disease activity, disease damage and age. The frequency of MetS was not significantly different from that of the control group, but almost half of the patients were found with this syndrome. PubMed, Int J rheumatologist Dis, 04/03/2018. (Also see Symptoms and Complications of Lupus) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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