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Smoking and systemic sclerosis (SSc): influence on microangiopathy and expression of anti-topoisomerase I antibodies (ATA) in a monocentric cohort. We observed a significant association between smoking history and positivity of ATA and we outlined the idea of a different effect of smoking on autoantibody expression between men and women. PubMed, Clin Exp Rheumatol, 03/25/2020. (Also see Antibodies and Preventive Care for Pulmonary Involvement) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.