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Characteristics of Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis and Anticentriole Autoantibodies (ACA). ACA-positive SSc-PAH rapidly deteriorates, so careful hemodynamic observation and timely aggressive use of pulmonary vasodilators should be considered. PubMed, Int Heart J, 2020;61(2):413-418. (Also see Antibodies and Pulmonary Hypertension Symptoms and Complications) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.

Pulmonary veno-occlusive disease (PVOD): a probably underdiagnosed cause of pulmonary hypertension in systemic sclerosis. Patients with PVOD usually have a poor prognosis and might experience acute pulmonary oedema after introduction of pulmonary vasodilators. PubMed, Clin Rheumatol, 01/22/2020. (Also see Pulmonary Hypertension Symptoms and Complications) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.