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The effects of upper and lower limb exercise on the microvascular reactivity in limited cutaneous systemic sclerosis (SSc) patients. Our results suggest that arm cranking has the potential to improve the microvascular endothelial function in SSc patients. PubMed, Arthritis Res Ther, 2018 Jun 5;20(1):112. (Also see Raynaud's: Rewarming Tips) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.