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Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers. The tear and salivary biomarkers identified could be implemented as potential non-invasive diagnostic tools that may aid in increasing diagnostic accuracy. PubMed, Arthritis Res Ther, 2019 Jul 31;21(1):181. (Also see Diagnosis of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.

Antibodies to aquaporins (AQPs) are frequent in patients with primary Sjögren’s syndrome (SS). Antibodies to AQPs (especially to AQP8 and AQP9) are frequent in SS patients and the likely important role of AQPs in salivary gland secretions justifies further research. Rheumatology, 08/31/2017. (Also see Diagnosis of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.

Beta-2 Microglobulin in Whole Unstimulated Saliva (sB2M) Can Effectively Distinguish Between Sjögren’s Syndrome (SS) and Non–Autoimmune Sicca Symptoms. In our setting, sB2M effectively distinguished between SS patients and non–autoimmune sicca symptoms and including sB2M in our conventional diagnostic arsenal may assist in the evaluation of patients in whom SS is suspected. Archives of Rheumatology, 06/08/2017. (Also see Diagnosis of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.