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Found 15 results

  1. Association between memory B–cells and clinical and immunological features of primary Sjögren's syndrome (pSS) and Sicca patients. It remains to be clarified whether Sicca patients with decreased memory B–cells represent pSS and if B–cell profiling could help in the diagnosis of pSS. PubMed, Rheumatol Int, 04/06/2018. (Also see Sjögren's Syndrome Research) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  2. Identification of a novel autoantibody against self–vimentin specific in secondary Sjögren's syndrome (sSS). This novel autoantibody is highly specific in the diagnosis of sSS, and the underlying molecular mechanism of the disease might be epitope spreading involved with vimentin. PubMed, Arthritis Res Ther, 2018 Feb 12;20(1):30. (Also see Diagnosis of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  3. Scoring hypoechogenic areas in one parotid and one submandibular gland increases feasibility of ultrasound in primary Sjögren's syndrome. Ultrasound examination of the parotid and submandibular glands on one side is sufficient to predict classification of patients according to the ACR–EULAR criteria. PubMed, Ann rheumatologist Dis, 12/11/2017. (Also see Diagnosis of Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  4. Severe intestinal dysbiosis is prevalent in primary Sjögren's syndrome (pSS) and is associated with systemic disease activity. Severe intestinal dysbiosis is a prevalent finding in pSS and is associated both with clinical and laboratory markers of systemic disease activity as well as gastrointestinal inflammation. PubMed, Arthritis Res Ther, 2017 Oct 24;19(1):237. (Also see Symptoms and Complications of Sjogren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  5. Association between objective signs and subjective symptoms of dry eye disease in patients with systemic sclerosis. A significant correlation was found between the Ocular Surface Disease Index (OSDI) as a subjective parameter and disease duration. PubMed, Rheumatol Int, 09/07/2017. (Also see Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  6. Systematic review and meta–analysis of the epidemiology of polyautoimmunity in Sjögren's syndrome (secondary Sjögren's syndrome (sSS)) focusing on autoimmune rheumatic diseases. Prevalence rates of sSS vary widely in different populations and the results of this meta–analysis highlight the need for better quality population studies. PubMed, Scand J Rheumatol, 2017 Sep 20:1-14. (Also see Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  7. Comorbidities in patients with Primary Sjögren's Syndrome (pSS) and Systemic Lupus Erythematosus (SLE): A comparative registries–based study. pSS patients have consistently less serious cardiovascular comorbidity burden and a lower prevalence of severe infection than those with SLE, although in contrast, their risk of lymphoma was greater. PubMed, Arthritis Care Res (Hoboken), 08/26/2016. (Also see Sjögren's Syndrome and Lupus in Overlap and Complications) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  8. Joelf

    Genetics in Sjögren's Syndrome.

    Genetics in Sjögren's Syndrome. The genes associated with Sjögren syndrome (SS) can be assigned to the NF–kB pathway, the IFN signaling pathway, lymphocyte signaling, and antigen presentation. Rheumatic Disease Clinics, 06/21/2016. (Also see Sjögren's Syndrome Research) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  9. Use of Biologics in Sjögren's Syndrome. In this review, we summarize the current evidence regarding B–cell targeted and anti–TNF therapies and provide an overview of promising drugs in the pipeline. Rheumatic Disease Clinics, 06/21/2016. (Also see Treatments for Symptoms of Sjögren's Syndrome and Biologic Agents) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  10. Illness Experiences in Women with Oral Dryness as a Result of Sjögren's Syndrome (pSS): The Patient Point of View. Xerostomia and other consequences of pSS can have a profound influence on daily life, however, the severity of the consequences depends on individual experiences with the illness, social influences and the psychological responses of the patient. Wiley Online Library, 04/06/2016. (Also see Sjögren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  11. Safety of treatments for primary Sjögren’s syndrome. Synthetic DMARDs have not shown much efficacy in earlier studies, while biologic DMARDs show promising results regarding efficacy and cause mostly mild adverse events. PubMed, Expert Opin Drug Saf, 01/25/2016. (Also see Treatments for Symptoms of Sjögren’s Syndrome and DMARDs) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  12. Dry Eye Disease Does Not Worsen With Time in Most Patients. Despite the general perception, dry eye disease does not necessarily worsen over time. Medscape, 12/30/2015. (Also see Symptoms and Complications of Sjogren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  13. Nailfold capillaroscopic findings in primary Sjögren's syndrome with and without Raynaud's phenomenon and/or positive anti-SSA/Ro and anti-SSB/La antibodies. Patients with RP associated with PSS had more dilated capillaries, but neither pericapillary haemorrhages nor capillary thrombosis was observed. PubMed, Rheumatol Int, 11/23/2015. (Also see Diagnosis of Primary Raynaud's using Nailfold Capillaroscopy and Diagnosis of Sjogren's Syndrome) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  14. Renal involvement in primary Sjögren's syndrome (SS). The prevalence of renal SS, its presentation, likely pathogenesis and treatment is reviewed in this article. PubMed, Rheumatology (Oxford), 2015 Sep;54(9):1541-8. (Also see Sjögren's Syndrome and B Cells And T Cells) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
  15. Amanda Thorpe has produced another video, entitled Overview of Sjogren's Syndrome in Systemic Scleroderma. Did you know the hallmark symptoms of Sjögren's include dry eyes, dry mouth, dry vagina, fatigue, and it can affect the skin, lungs, heart, kidneys, muscles, and central nervous system. (Also see Scleroderma Videos, Amanda Thorpe and How to Volunteer) Posted 05/03/2015. This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.
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