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Hi, I have after my 40ies developed problems with numbness of my hands, Raynauds and autoantibodies with centromeric pattern as well as some mostly mild problems with arthritis and tendinitis. Suspicion is systemic sclerosis, but too early for a diagnosis. I hardly have any skin involvement. And nail capillary microscopy was uncertain, vessels looked borderline normal. A year ago the numbness of my hands, which mainly happened during night or while riding a bike, reading a book - anything requiring elevation of my arms or flexing of my wrist - took a new course. Before it had been lookin