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peanut

Imuran

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Hi everyone,

Well I just got back from my rheumys and things appear well. I just finished 6 months of IV cytoxan without any major problems and my pft show that my lungs seem to be stabilizing and my DLCO is up. Hooray. Today, I start Imuran. I asked my rheumatologist how do I know if its not working and he says by the pft, but there are probably other indicators – right? I’d love to hear anyone’s experience with Imuran.

 

peanut


You can deprive the body but the soul needs chocolate

my HMO makes me wear a helmet...

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Hi Peanut,

 

Thanks for the update. I am so glad to hear that your PFT numbers look stable--that is great news! I sure hope the Imuran works well for you. When do you start it? Do keep us posted.

 

Warm wishes,

Heidi

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Heidi,

I took my first pill this morning. I also started Salagen for dry mouth and maybe it's just me but my mouth already feels better - or I just could be feeling overly happy and optimistic after my doctor's appt.

 

peanut


You can deprive the body but the soul needs chocolate

my HMO makes me wear a helmet...

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Peanut,

Congratulations on the PFT's! I'm so glad the IV cytoxan worked for you. It sounds like you didn't really have much side effect from it. Another great thing.

Remember that Imuran is an immunosuppresant and since you are taking it orally, it might take a few weeks or even a few months to feel or see any effects from it. I did find the following study for IV Cytoxan followed with Imuran (azathioprine)

 

A multicenter, prospective, randomized, double-blind, placebo-controlled trial of corticosteroids and intravenous cyclophosphamide followed by oral azathioprine for the treatment of pulmonary fibrosis in scleroderma.

 

Statement from the study's conclusion:

"This suggests that treatment of pulmonary fibrosis in SSc with low-dose prednisolone and IV CYC followed by AZA stabilizes lung function in a subset of patients with the disease." (Encouraging!)

 

Keep us informed on how you're doing.

 

Big Hugs,


Janey Willis

ISN Support Specialist

(Retired) ISN Assistant Webmaster

(Retired) ISN News Director

(Retired) ISN Technical Writer for Training Manuals

International Scleroderma Network (ISN)

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