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Joelf

Acute myeloid leukemia developing in patients with autoimmune diseases.

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Acute myeloid leukemia developing in patients with autoimmune diseases.

The risk of developing therapy-related acute myeloid leukemia also applies to patients with non-malignant conditions such as autoimmune diseases treated with cytotoxic and/or immunosuppressive agents. PubMed. Haematologica. 2011 Dec 16. (Also see: Cyclophosphamide)

This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles.


Jo Frowde

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When I read this article I found it very interesting and I thought "Uh-oh" as I had 6 infusions of Cyclophosphamide for my interstitial lung disease. At the time my consultant did advise me that they only really liked to use it for a maximum of 6 infusions as it was so powerful but in my case it did do the job very successfully so I consider that the risk was worth it!

 

It certainly is a drug to be treated with respect, though!! ;)


Jo Frowde

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I'm currently on daily oral cyclophosphamide and hope to switch to Mycophenolate for my ILD. The doctors did inform me of the potential side effects (also bladder cancer with the oral cyclophosphamide) but most immediate concern now is stopping the sclero lung progression. It is good to be informed and weigh the risk/benefit.

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Hello Jo

 

I really think you made the right call given how well you are now compared to how ill you would be!

 

Hello Bleev

 

Yep, it pays to be informed, we may still make the same decision but at least we know what we are potentially agreeing to.

 

Take care.


Amanda Thorpe

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Hi Bleev,

 

I do hope the Cyclophosphamide will be successful for you; do let us know how you get on with it, won't you?

 

Thanks Amanda,

 

I have been incredibly fortunate with the result I obtained from the Cyclophosphamide infusions as my consultant was determined to treat my ILD very aggressively. I went to The Royal Brompton last week and my TLCO was 85%. My consultant was very pleased and said that they could pull people in off the street with worse lung function tests than I had now due to the administration of this drug! ;) :emoticons-yes:

 

How can I ever thank them enough?!


Jo Frowde

ISN Assistant Webmaster

SD World Webmaster

ISN Sclero Forums Manager

ISN News Manager

ISN Hotline Support Specialist

ISN Chat Host

International Scleroderma Network (ISN)

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Thank you Jo and Amanda!

 

Jo, Congratulations on your AWESOME news and thank you for sharing it!

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