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Salivary mucins induce a Toll-like receptor 4 (TLR4)-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren's syndrome (SS)?

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Salivary mucins induce a Toll-like receptor 4 (TLR4)-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren's syndrome (SS)?

 

Salivary mucins were recognized by TLR4 in epithelial cells initiating a pro-inflammatory response and thereby contribute to the development of a chronic state characteristic of SS. PubMed, Rheumatology (Oxford), 03/22/2015. (Also see Sjogren's Syndrome Research)

 

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