Jfuchs1981

SCL-70 Positive-2.6 score: What does it mean?

5 posts in this topic

I'm a 35 years old male who was healthy as an ox 2 months ago. After my grandfather passed, and a 3 day virus I started having these weird symptoms that began in my GI tract. After countless CT scans, blood testing, endoscopies, etc they diagnosed me gastroparesis. A month later I started having significant pain under my sternum thus hospital visit. Post a seven day stay, all tests came back negative, another endoscopy, now a normal gastric emptying test, and an esopheagram that showed very minor dysmotility when swallowing a pill, which passed with one sip of water. Referred to a neurologist who ordered and autoimmune panel. All came back negative, including ANA-IFA test except a positive SCL-70 score of 2.6. I have no Raynaud's, no skin presentation, no lung problems, no heart problems, etc. Does this mean it's definitely pre-Scleroderma because of the test and I'll eventually get this rare disease? I have an appt in Weston, FL at a Scleroderma specialized clinic in two weeks. Just concerned that this debilitating disease is lying dormant ready to attack in my body.

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Hi Jfuchs,

 

Welcome to these forums!

 

I'm sorry to hear that you've been suffering with worrying symptoms and a positive blood test.

 

Unfortunately, one of the problems with scleroderma is that it is very difficult to diagnose, not least because the way it presents itself is so diverse and it affects everyone differently. It is quite possible to have positive blood tests for the disease and yet never go on to develop it fully and vice versa. It is equally possible that the symptoms you describe could relate to other diseases and not only to scleroderma.

 

I'm pleased to hear that you have an appointment at a scleroderma clinic; we do recommend that our members, if possible, consult a listed scleroderma expert, as this complex disease does require specialist knowledge and expertise.

 

Please do keep us posted on the results of your appointment at the scleroderma clinic.

 

Kind regards,


Jo Frowde

ISN Assistant Webmaster

SD World Webmaster

ISN Sclero Forums Manager

ISN News Manager

ISN Hotline Support Specialist

International Scleroderma Network (ISN)

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Hi Jfuchs,

 

Welcome to Sclero Forums!  I'm sorry you are having health problems and tested positive for SCL-70. It's good that you will be seeing a rheumatologist. I hope they are helpful. Please keep in touch and let us know how things go.

 

:hug-group:


Warm Hugs,

 

Shelley Ensz

Founder and President

International Scleroderma Network (ISN)

Hotline and Donations: 1-800-564-7099

 

The most important thing in the world to know about scleroderma is sclero.org.

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It is very possible that you test positive for SCL-70 but do not and will not develop Scleroderma.  Antibody testing can be tricky and show results that are not true, such as sine and vice versa.  Hang in there, you have been in a stressful situation with your grandfather, I have high hopes the test is an anomaly :)


Diffuse Scleroderma Diagnosed March 2009

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The SCL70 is likely a false positive especially with that low number.  A negative ANA by IFA, with no Raynauds and no Skin thickening essentially rules out a diagnosis of scleroderma.  

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