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Viral infections could be the most likely, but it is possible.  You need to request an antinuclear antibody test, which would give a clue as to whether it is scleroderma or any other autoimune disease.

Do you have any other relevant symptoms?

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Hi Clementine,


As per our medical page on B Cells and T Cells, in the thymus gland, lympohocytes are matured into T cells. Sometimes T cells become overactive, which is suspected as being part of the process that leads to autoimmune diseases.


The best person to advise you about the low lymphocytes in your blood tests is your scleroderma specialist.


Kind regards,

Jo Frowde

ISN Assistant Webmaster

SD World Webmaster

ISN Sclero Forums Manager

ISN News Manager

ISN Hotline Support Specialist

International Scleroderma Network (ISN)

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I do have systemic sine scleroderma, Sjogren’s and ILD.   I don’t recall being so low and I have had a lot of labs.  I always thought our WBC was elevated with autoimmune diseases.  I’m going to check out the link.  I can ask my dr but the appt is a month away and I am curious.   

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