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Positive anti-SCL-70 antibody.

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Hi everyone,


I am a 29 year old with 3 little girls under the age of three. I have a history of juvenile rheumatoid arthritis(remission) hypothyroidism and micro colitis, but I am actually a pretty healthy lady and have a normal busy life! I have had  chronic hives for over 3 months and went to my family doctor for the same who referred me to a specialist. They did lots of blood work and my ANA and anti-SCL-70 came back as positive today (my family doctor let me know). I have no symptoms of scleroderma.  


I am so scared I can hardly think.  I don’t have another appointment with the specialist for 4 weeks but I need to get in to see him; I can’t live like this.  I can’t imagine not being able to care for my family.  Does anyone know if this could be a mistake ? Can you live a normal life with this disease ? 

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Hi Kristinj,


Welcome to these Forums!


I'm sorry to hear that you've had worrying blood tests. Please refer to our sticky thread regarding the importance of blood test results.


I can understand your concern about developing scleroderma, particularly as you have other autoimmune problems and a young family to consider. However, because of the complex nature of the disease it is extremely difficult to obtain a definite diagnosis and it's quite possible that your scleroderma expert/rheumatologist will suggest that you wait and see what transpires, pending you developing any more symptoms. It is possible to have false positive results, but the best person to explain the results of your blood tests is your doctor. 


In the event of actually developing scleroderma, it is perfectly possible to live a "normal" life (whatever that is! :wink:) but for the time being in the absence of any more symptoms, I would suggest that you concentrate on your family and try not to worry too much about what might happen (easy to say, I know). I remember when I was first diagnosed I was wanting more than anything to be reassured that everything would be alright, but of course without second sight my consultants were unable to do this. However, I'm still alive after ten years and have no plans to peg out anytime soon (barring my being run over by a bus, or some such eventuality! :wink:)


Please post again and let us know how you get on with your specialist appointment in four weeks time.


Kind regards,

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