Joelf Posted June 25 Distal radius and tibia bone microarchitecture impairment in female patients with diffuse systemic sclerosis (dSSc). Bone microarchitecture in patients with dSSc showed impairment of trabecular and cortical bone at distal radius and tibia and variables associated with hand involvement and disease duration may be considered prognostic factors of this bone impairment. PubMed, Osteoporos Int, 04/27/2019. (Also see Osteoporosis) This item was posted in the ISN Newsroom. Please check the newsroom daily for updates on scleroderma and other related articles. Quote Jo Frowde ISN Board Member ISN Secretary of the Board ISN Assistant Webmaster SD World Webmaster ISN Sclero Forums Manager ISN News Manager ISN Hotline Support Specialist International Scleroderma Network (ISN) Share this post Link to post Share on other sites