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Positive but no symptoms?

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Based on those of you with positive results and well knowledgable on ANA and ENA results, is it possible to be Centromere- B positive and still be healthy and asymptomatic? I know it is associated with limited Sclero , but I was wondering if it's a "severely" symptomatic form of scleroderma?

 

I tested positive 10 months ago accidentally and thank goodness, I dont manifest clinical symptoms, not even Raynaud's, hence the confusion. Could it only accumulate to Raynaud's and never get worse? A few months later, I was tested again and they found me to be Anti-SM positive, which is highly lupus specific. Should I be worried? I'm honestly very terrified, these tests are mind boggling, and I wish I didn't figure this out accidentally .

 

Thanks for your help, blessings.

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Hi Omer

Yes it is possible to test positive and have no symptoms or have symptoms appear many years later.

If you have no symptoms though, I would have to ask why you were given the blood tests.

My first ANA test was done when I went to my general practitioner with Raynauds, although I had been having related problems for nearly a year before they finally realised that my symptoms were not imaginary and that I was not insane.

I hope you continue to remain sympom free though.

Best wishes, Dimarzio

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Hi,

One day I had nerve like pain running down my legs and arms due to some studying stress at the time. And I had visited my general practitioner for some help, and he decided to order the blood panel and it said centromere B 4.7. However, literally after 1 month it went away. I think it was my stress because thank goodness it hasn't come back since. It felt like a billion bees stinging my legs - just my legs. Then he referred me to a rheumatologist. The rheumatologist a few months later ordered an ANA and ENA panel. I then got my results and voila, completely different results : it was ANA 1:320 ; homogenous ; Anti-SM positive only .

 

This was all 10 months ago, I display no actual clinical symptoms. So should I worry? I know anti-sm if very specific to Lupus - my rheumatologist said in a year or so if I don't manifest lupus symptoms, then just don't worry. And no, I have no Raynaud's, no color change with weather/temperature as well. 

 

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Hi Omer,

 

Welcome to these forums!

 

I'm sorry to hear that you've had worrying blood test results. Please see our sticky on the subject of blood tests and symptoms (or lack of them.)

 

The best person to advise you about your blood test results is your rheumatologist.

 

Kind regards,


Jo Frowde

ISN Board Member

ISN Secretary of the Board

ISN Assistant Webmaster

SD World Webmaster

ISN Sclero Forums Manager

ISN News Manager

ISN Hotline Support Specialist

International Scleroderma Network (ISN)

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