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Scleroderma-specific autoantibodies embedded in immune complexes (ICs) mediate endothelial damage: an early event in the pathogenesis of systemic sclerosis.


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Scleroderma-specific autoantibodies embedded in immune complexes (ICs) mediate endothelial damage: an early event in the pathogenesis of systemic sclerosis.

 

These data provide the first demonstration of the pathogenicity of ICs from scleroderma patients with different autoantibodies on the endothelium. PubMed, Arthritis Res Ther, 2020 Nov 9;22(1):265. (Also see Antibodies)

 

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