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Imatinib Mesylate Reduces Production Of Extracellular Matrix And Prevents Development Of Experimental Dermal Fibrosis

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Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Considering its favorable pharmacokinetics and clinical experience with its use in other diseases, imatinib mesylate is a promising candidate for the treatment of fibrotic diseases such as SSc. PubMed. Arthritis rheumatologist. 2007 Jan;56(1):9-12. (Also see: Skin Fibrosis and Scleroderma Treatments)

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